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Details on Person NF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activity

Class:IdLiteratureReference:451627
_displayNameNF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activity
_timestamp2010-01-07 17:03:59
author[Person:451599] Beinke, S
[Person:451655] Deka, J
[Person:451602] Lang, V
[Person:451625] Belich, MP
[Person:350977] Walker, PA
[Person:450454] Howell, S
[Person:182810] Smerdon, SJ
[Person:351007] Gamblin, SJ
[Person:451594] Ley, SC
created[InstanceEdit:451629] Jupe, S, 2010-01-07
journalMol Cell Biol
pages4739-52
pubMedIdentifier12832462
titleNF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activity
volume23
year2003
(literatureReference)[Summation:5684249] Tumor progression locus-2 (TPL2, also known as COT and MAP3K...
[Summation:5687814] IKBKB-induced proteolysis of NFkB p105 to p50 releases MAP3K...
[Reaction:451634] NFKB p105, TPL2 (COT) and ABIN2 form a stable complex [Homo sapiens]
[BlackBoxEvent:5684273] 3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 [Homo sapiens]
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