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Details on Person Dual effects of IkappaB kinase beta-mediated phosphorylation on p105 Fate: SCF(beta-TrCP)-dependent degradation and SCF(beta-TrCP)-independent processing
| Class:Id | LiteratureReference:451620 |
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| _displayName | Dual effects of IkappaB kinase beta-mediated phosphorylation on p105 Fate: SCF(beta-TrCP)-dependent degradation and SCF(beta-TrCP)-independent processing |
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| _timestamp | 2010-01-07 16:16:39 |
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| author | [Person:444240] Cohen, S
[Person:451623] Achbert-Weiner, H
[Person:183093] Ciechanover, A |
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| created | [InstanceEdit:451618] Jupe, S, 2010-01-07 |
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| journal | Mol Cell Biol |
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| pages | 475-86 |
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| pubMedIdentifier | 14673179 |
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| title | Dual effects of IkappaB kinase beta-mediated phosphorylation on p105 Fate: SCF(beta-TrCP)-dependent degradation and SCF(beta-TrCP)-independent processing |
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| volume | 24 |
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| year | 2004 |
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| (literatureReference) | [Reaction:5684248] SCF betaTrCP1,2 binds p-NFkB p105:TPL2:ABIN2 [Homo sapiens]
[Reaction:5684250] SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 [Homo sapiens]
[CatalystActivityReference:9643613] ubiquitin-protein transferase activity of SCF-beta-TrCP1,2:p-S927,S932-NFKB1:p-S,T-MAP3K8:TNIP2 [cytosol] Dual effects of IkappaB kinase beta-mediated phosphorylation on p105 Fate: SCF(beta-TrCP)-dependent degradation and SCF(beta-TrCP)-independent processing |
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