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Details on Person Jupe, S, 2010-01-06

Class:IdInstanceEdit:451610
_displayNameJupe, S, 2010-01-06
_timestamp2010-01-06 16:49:52
author[Person:391309] Jupe, Steve
dateTime2010-01-06 21:49:41
(created)[Summation:451606] IKK-mediated NFkB p105 phosphorylation generates a binding s...
[EntityWithAccessionedSequence:451607] NFKB1(1-968) [cytosol] [Homo sapiens]
[ModifiedResidue:451608] O-phospho-L-serine at 927
[EntityWithAccessionedSequence:451611] p-S927,S932-NFKB1(1-968) [cytosol] [Homo sapiens]
[CatalystActivity:451612] IkappaB kinase activity of IKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB [cytosol]
[ModifiedResidue:451613] O-phospho-L-serine at 932
[Complex:451614] SCF betaTrCP complex:p-NFKB p105 [cytosol] [Homo sapiens]
(modified)[EntityWithAccessionedSequence:168172] RELA [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:174237] BTRC [cytosol] [Homo sapiens]
[Complex:206842] NFKB1(1-433):RELA:p-S32,S36-NFKBIA [cytosol] [Homo sapiens]
[Complex:206891] NFKB1(1-433):RELA:p-S32,S36-NFKBIA:BTRC:CUL1:RBX1:SKP1 [cytosol] [Homo sapiens]
[BlackBoxEvent:209061] Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex [Homo sapiens]
[Reaction:209063] Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex [Homo sapiens]
[Reaction:209087] IKBA is phosphorylated by Phospho IKKB kinase [Homo sapiens]
[Reaction:209125] SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex [Homo sapiens]
[Pathway:446652] Interleukin-1 family signaling [Homo sapiens]
[Summation:451598] NFkappaB p105 protein (p105) is a precursor of the NFkappaB ...
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No pathways have been reviewed or authored by Jupe, S, 2010-01-06 (451610)