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Details on Person Jupe, S, 2010-01-06

Class:IdInstanceEdit:451601
_displayNameJupe, S, 2010-01-06
_timestamp2010-01-06 15:23:01
author[Person:391309] Jupe, Steve
dateTime2010-01-06 20:22:45
(created)[Person:451594] Ley, SC
[LiteratureReference:451595] betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932
[Person:451596] Janzen, J
[Person:451597] Hay, RT
[Summation:451598] NFkappaB p105 protein (p105) is a precursor of the NFkappaB ...
[Person:451599] Beinke, S
[Person:451600] Salmeron, A
[Person:451602] Lang, V
[Person:451604] Soneji, Y
[Person:451605] Fischer, GZ
(modified)[EntityWithAccessionedSequence:168168] NFKB1(1-433) [cytosol] [Homo sapiens]
[BlackBoxEvent:209061] Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex [Homo sapiens]
[Reaction:209063] Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex [Homo sapiens]
[Reaction:209087] IKBA is phosphorylated by Phospho IKKB kinase [Homo sapiens]
[Reaction:209125] SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex [Homo sapiens]
[Pathway:446652] Interleukin-1 family signaling [Homo sapiens]
[Summation:447016] Within the TAK1 complex (TAK1 plus TAB1 and TAB2/3) activate...
[Summation:450184] The TAK1 complex consists of Transforming growth factor-beta...
[CatalystActivity:450188] MAP kinase kinase kinase activity of TAK1 complex [cytosol]
[Summation:451573] NF-kappa-B essential modulator (NEMO, also known as IKKG abb...
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No pathways have been reviewed or authored by Jupe, S, 2010-01-06 (451601)