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Details on Person NFkappaB p105 protein (p105) is a precursor of the NFkappaB ...
| Class:Id | Summation:451598 |
|---|---|
| _displayName | NFkappaB p105 protein (p105) is a precursor of the NFkappaB ... |
| _timestamp | 2010-02-08 15:43:47 |
| created | [InstanceEdit:451601] Jupe, S, 2010-01-06 |
| modified | [InstanceEdit:451610] Jupe, S, 2010-01-06 [InstanceEdit:507710] Jupe, S, 2010-02-08 |
| text | NFkappaB p105 protein (p105) is a precursor of the NFkappaB p50 subunit and an inhibitor of NFkappaB. The IkappaB kinase (IKK) complex phosphorylates p105 on S927 within the PEST region. TNF-alpha-induced p105 proteolysis additionally requires the phosphorylation of S932. Purified IKK (IKK1) or IKKB (IKK2) can phosphorylate both these regulatory serines in vitro. |
| (summation) | [Reaction:5684267] IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex [Homo sapiens] |
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No pathways have been reviewed or authored by NFkappaB p105 protein (p105) is a precursor of the NFkappaB ... (451598)
