Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person NEMO binds polyubiquitinated IRAK1

Class:IdReaction:451561
_displayNameNEMO binds polyubiquitinated IRAK1
_doReleaseTRUE
_timestamp2017-09-11 14:11:48
authored[InstanceEdit:744679] Ray, KP, 2010-05-17
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:451558] Jupe, S, 2010-01-05
edited[InstanceEdit:744683] Jupe, S, 2010-05-17
input[Complex:168113] CHUK:IKBKB:IKBKG [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:451565] K63polyUb-hp-IRAK1 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:451426] Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase
modified[InstanceEdit:744684] Jupe, S, 2010-05-17
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9020703] Jupe, Steve, 2017-09-11
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNEMO binds polyubiquitinated IRAK1
output[Complex:451560] Poly-K6-Ub-hp-IRAK1:CHUK:IKBKB:IKBKG [cytosol] [Homo sapiens]
releaseDate2010-06-15
reviewed[InstanceEdit:744680] Pinteaux, E, 2010-05-17
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1105791] R-HSA-451561.3
summation[Summation:451573] NF-kappa-B essential modulator (NEMO, also known as IKKG abb...
(hasEvent)[Pathway:9020702] Interleukin-1 signaling [Homo sapiens]
(updatedInstance)[_UpdateTracker:9790048] Update Tracker - [Reaction:451561] NEMO binds polyubiquitinated IRAK1 - v35:[modifyText]
[Change default viewing format]
No pathways have been reviewed or authored by NEMO binds polyubiquitinated IRAK1 (451561)
Follow Reactome