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Details on Person activated MEK2 phosphorylates ERK2

Class:Id	Reaction:451516
_displayName	activated MEK2 phosphorylates ERK2
_doRelease	TRUE
_timestamp	2010-12-02 14:35:42
authored	[InstanceEdit:438031] Shamovsky, V, 2009-09-22
catalystActivity	[CatalystActivity:451515] protein serine/threonine kinase activity of phospho MEK2 : ERK2 [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:451501] Shamovsky, V, 2010-01-05
edited	[InstanceEdit:668815] Shamovsky, V, 2010-05-04
inferredFrom	[Reaction:109862] MAP2K2 phosphorylates MAPK1 [Homo sapiens]
input	[Complex:451495] phospho MEK2 : ERK2 [cytosol] [Gallus gallus] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:517851] Flagellin and lipopolysaccharide stimulate the MEK-ERK signaling pathway in chicken heterophils through differential activation of the small GTPases, Ras and Rap1 [LiteratureReference:571255] Flagellin and lipopolysaccharide up-regulation of IL-6 and CXCLi2 gene expression in chicken heterophils is mediated by ERK1/2-dependent activation of AP-1 and NF-kappaB signaling pathways
modified	[InstanceEdit:571393] Shamovsky, V, 2010-04-09 [InstanceEdit:844697] Shamovsky, V, 2010-05-28 [InstanceEdit:1004540] D'Eustachio, P, 2010-11-09 [InstanceEdit:1008271] Shamovsky, V, 2010-11-10 [InstanceEdit:1063713] Shamovsky, V, 2010-11-25 [InstanceEdit:1094880] Shamovsky, V, 2010-11-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	activated MEK2 phosphorylates ERK2
output	[Complex:451480] phospho ERK2 : phospho MEK2 [cytosol] [Gallus gallus] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:451482] activated MEK2 binds ERK2 [Gallus gallus]
releaseDate	2010-12-14
reviewed	[InstanceEdit:977269] D'Eustachio, P, 2010-10-15
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:1104750] R-GGA-451516.2
summation	[Summation:1094356] Chicken ERK2 shares 99% of amino acid sequence identity with...
(hasEvent)	[Pathway:451478] ERK activation [Gallus gallus]
(precedingEvent)	[Reaction:451505] Dissociation of phospho ERK2 :phospho MEK2 complex [Gallus gallus]
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No pathways have been reviewed or authored by activated MEK2 phosphorylates ERK2 (451516)