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Details on Person Dissociation of phospho ERK2 :phospho MEK2 complex

Class:Id	Reaction:451505
_displayName	Dissociation of phospho ERK2 :phospho MEK2 complex
_doRelease	TRUE
_timestamp	2010-12-02 14:36:10
authored	[InstanceEdit:438031] Shamovsky, V, 2009-09-22
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:451501] Shamovsky, V, 2010-01-05
edited	[InstanceEdit:668815] Shamovsky, V, 2010-05-04
inferredFrom	[Reaction:109864] Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 [Homo sapiens]
input	[Complex:451526] phospho ERK2 : phospho MEK2 [cytosol] [Gallus gallus]
isChimeric	FALSE
literatureReference	[LiteratureReference:517851] Flagellin and lipopolysaccharide stimulate the MEK-ERK signaling pathway in chicken heterophils through differential activation of the small GTPases, Ras and Rap1 [LiteratureReference:571255] Flagellin and lipopolysaccharide up-regulation of IL-6 and CXCLi2 gene expression in chicken heterophils is mediated by ERK1/2-dependent activation of AP-1 and NF-kappaB signaling pathways
modified	[InstanceEdit:573301] Shamovsky, V, 2010-04-09 [InstanceEdit:674720] Shamovsky, V, 2010-05-05 [InstanceEdit:674722] Shamovsky, V, 2010-05-05 [InstanceEdit:1004540] D'Eustachio, P, 2010-11-09 [InstanceEdit:1008271] Shamovsky, V, 2010-11-10 [InstanceEdit:1063713] Shamovsky, V, 2010-11-25 [InstanceEdit:1094365] Shamovsky, V, 2010-11-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Dissociation of phospho ERK2 :phospho MEK2 complex
output	[EntityWithAccessionedSequence:451487] phospho MEK2 [cytosol] [Gallus gallus] [EntityWithAccessionedSequence:451523] phospho-ERK2 [cytosol] [Gallus gallus]
precedingEvent	[Reaction:451516] activated MEK2 phosphorylates ERK2 [Gallus gallus] [Reaction:451482] activated MEK2 binds ERK2 [Gallus gallus]
releaseDate	2010-12-14
reviewed	[InstanceEdit:977269] D'Eustachio, P, 2010-10-15
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:1104840] R-GGA-451505.2
summation	[Summation:1094363] MEK-ERK pathways are considered to be highly conserved. Thei...
(hasEvent)	[Pathway:451478] ERK activation [Gallus gallus]
(precedingEvent)	[Reaction:451535] Dimerization of activated ERK2 [Gallus gallus]
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No pathways have been reviewed or authored by Dissociation of phospho ERK2 :phospho MEK2 complex (451505)