Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Auto ubiquitination of oligo TRAF6 bound to p-IRAK2

Class:Id	BlackBoxEvent:451450
_displayName	Auto ubiquitination of oligo TRAF6 bound to p-IRAK2
_doRelease	TRUE
_timestamp	2010-12-02 14:36:21
authored	[InstanceEdit:451580] Shamovsky, V, 2010-01-05
catalystActivity	[CatalystActivity:451446] ubiquitin-protein transferase activity of oligo TRAF6 : p-IRAK2 [plasma membrane]
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:451437] Shamovsky, V, 2010-01-05
edited	[InstanceEdit:994006] Shamovsky, V, 2010-11-05
inferredFrom	[Reaction:202453] Auto-ubiquitination of TRAF6 [Homo sapiens]
input	[DefinedSet:434147] Ubiquitin [cytosol] [Gallus gallus] [DefinedSet:434147] Ubiquitin [cytosol] [Gallus gallus] [DefinedSet:434147] Ubiquitin [cytosol] [Gallus gallus] [DefinedSet:434147] Ubiquitin [cytosol] [Gallus gallus] [DefinedSet:434147] Ubiquitin [cytosol] [Gallus gallus] [DefinedSet:434147] Ubiquitin [cytosol] [Gallus gallus] [DefinedSet:434147] Ubiquitin [cytosol] [Gallus gallus] [DefinedSet:434147] Ubiquitin [cytosol] [Gallus gallus] [DefinedSet:434147] Ubiquitin [cytosol] [Gallus gallus] [Complex:451475] oligo TRAF6 : p-IRAK2 [plasma membrane] [Gallus gallus]
literatureReference	[LiteratureReference:202511] Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation
modified	[InstanceEdit:434572] Shamovsky, V, 2009-08-31 [InstanceEdit:446250] Shamovsky, V, 2009-11-11 [InstanceEdit:451967] Shamovsky, V, 2010-01-14 [InstanceEdit:532628] Shamovsky, V, 2010-03-01 [InstanceEdit:571308] Shamovsky, V, 2010-04-09 [InstanceEdit:975831] Shamovsky, V, 2010-10-04 [InstanceEdit:977266] D'Eustachio, P, 2010-10-15 [InstanceEdit:1008271] Shamovsky, V, 2010-11-10 [InstanceEdit:1047533] Shamovsky, V, 2010-11-23 [InstanceEdit:1063706] Shamovsky, V, 2010-11-25 [InstanceEdit:1094365] Shamovsky, V, 2010-11-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Auto ubiquitination of oligo TRAF6 bound to p-IRAK2
output	[Complex:451453] pUb oligo TRAF6 : p-IRAK2 [plasma membrane] [Gallus gallus]
precedingEvent	[Reaction:451466] TRAF6 binding to activated IRAK2 stimulates its oligomerization [Gallus gallus] [Reaction:434084] p-IRAK2- TRAF6 dissociates from the activated chTLR complex [Gallus gallus]
releaseDate	2010-12-14
requiredInputComponent	[Complex:433960] UBE2N : UBE2V complex [cytosol] [Gallus gallus]
reviewed	[InstanceEdit:977269] D'Eustachio, P, 2010-10-15
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:1104875] R-GGA-451450.2
summation	[Summation:202446] TRAF6 possesses ubiquitin ligase activity and undergoes K-63...
(hasEvent)	[Pathway:433822] NFkB and MAPK activation mediated by TRAF6 [Gallus gallus]
(precedingEvent)	[Reaction:451463] pUb_TRAF6 pIRAK2 recruits TAK1 kinase complex [Gallus gallus] [BlackBoxEvent:451470] Activated chicken TRAF6 synthesizes free K63bound poly_Ub chains within the complex p-IRAK2:pUb_oligo TRAF6 [Gallus gallus]
(updatedInstance)	[_UpdateTracker:9788119] Update Tracker - [BlackBoxEvent:451450] Auto ubiquitination of oligo TRAF6 bound to p-IRAK2 - v43:[modifyText] [_UpdateTracker:9789950] Update Tracker - [BlackBoxEvent:451450] Auto ubiquitination of oligo TRAF6 bound to p-IRAK2 - v36:[modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by Auto ubiquitination of oligo TRAF6 bound to p-IRAK2 (451450)