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Details on Person Activated TLR7 or 21 recruits MyD88

Class:Id	Reaction:451439
_displayName	Activated TLR7 or 21 recruits MyD88
_doRelease	TRUE
_timestamp	2011-03-02 09:06:35
authored	[InstanceEdit:1094913] Shamovsky, V, 2010-11-30
compartment	[Compartment:74700] endosome membrane [Compartment:70101] cytosol
created	[InstanceEdit:451437] Shamovsky, V, 2010-01-05
edited	[InstanceEdit:1221606] Shamovsky, V, 2011-02-24
inferredFrom	[Reaction:975175] MyD88 interacts with the activated TLR receptor 7, 8 or 9 [Homo sapiens]
input	[EntityWithAccessionedSequence:433987] MyD88 [cytosol] [Gallus gallus] [EntityWithAccessionedSequence:433987] MyD88 [cytosol] [Gallus gallus] [DefinedSet:573279] activated TLR7 or 21 bound to ligand [endosome membrane] [Gallus gallus]
isChimeric	FALSE
literatureReference	[LiteratureReference:434143] Molecular cloning and expression analysis of chicken MyD88 and TRIF genes [LiteratureReference:571177] Molecular cloning and functional characterization of a novel isoform of chicken myeloid differentiation factor 88 (MyD88)
modified	[InstanceEdit:571297] Shamovsky, V, 2010-04-09 [InstanceEdit:994004] Shamovsky, V, 2010-11-05 [InstanceEdit:1216498] Shamovsky, V, 2011-02-14 [InstanceEdit:1220566] Shamovsky, V, 2011-02-21 [InstanceEdit:1221614] Shamovsky, V, 2011-02-24 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Activated TLR7 or 21 recruits MyD88
output	[Complex:451459] activated TLR7/ or TLR21 : MyD88 complex [endosome membrane] [Gallus gallus]
precedingEvent	[Reaction:451506] TLR21homodimer binds to DNA [Gallus gallus] [Reaction:451481] TLR7 binds to recognized ligands [Gallus gallus]
releaseDate	2011-03-15
reviewed	[InstanceEdit:1112618] D'Eustachio, P, 2010-12-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:1224896] R-GGA-451439.2
summation	[Summation:571170] Cloning and analysis of full length chicken MyD88 revealed a...
(hasEvent)	[Pathway:451477] MyD88-dependent cascade initiated on endosome membrane [Gallus gallus]
(precedingEvent)	[Reaction:451461] IRAK4 binds to the activated TLR7 or 21 [Gallus gallus]
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No pathways have been reviewed or authored by Activated TLR7 or 21 recruits MyD88 (451439)