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Details on Person Interaction of IQGAP1 with nephrin

Class:Id	Reaction:451377
_displayName	Interaction of IQGAP1 with nephrin
_doRelease	TRUE
_timestamp	2012-03-23 14:58:07
authored	[InstanceEdit:214881] de Bono, B, Garapati, P V, 2008-02-26 12:30:30
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:451394] Garapati, P V, 2010-01-05
edited	[InstanceEdit:532602] Garapati, P V, 2010-03-01
entityOnOtherCell	[EntityWithAccessionedSequence:197692] NPHS1-1 [plasma membrane] [Homo sapiens]
input	[EntityWithAccessionedSequence:381681] IQGAP1 [plasma membrane] [Homo sapiens] [Complex:373679] NPHS1 dimer:KIRREL [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:451389] Characterization of the interactions of the nephrin intracellular domain [LiteratureReference:373484] Nephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin-Darby canine kidney cells expressing nephrin [LiteratureReference:451378] Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein complex [LiteratureReference:936072] Gastric hyperplasia in mice lacking the putative Cdc42 effector IQGAP1
modified	[InstanceEdit:451759] Garapati, P V, 2010-01-11 [InstanceEdit:532597] Garapati, P V, 2010-03-01 [InstanceEdit:765030] Garapati, P V, 2010-05-20 [InstanceEdit:847688] Garapati, P V, 2010-05-30 [InstanceEdit:933340] Garapati, P V, 2010-08-10 [InstanceEdit:936071] Garapati, P V, 2010-08-22 [InstanceEdit:2167920] Garapati, P V, 2012-03-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Interaction of IQGAP1 with nephrin
output	[Complex:451398] Nephrin dimer:IQGAP1 [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:373714] Cis-Heterodimerization of nephrin and KIRREL [Homo sapiens] [Reaction:373732] Nephrin trans-homophilic interaction [Homo sapiens]
releaseDate	2010-09-21
reviewed	[InstanceEdit:765028] Huber, TB, Grahammer, Florian, 2010-05-20
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104398] R-HSA-451377.2
summation	[Summation:451397] IQGAP1, an effector protein of the small GTPases Rac1 and Cd...
(hasEvent)	[Pathway:373753] Nephrin family interactions [Homo sapiens]
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No pathways have been reviewed or authored by Interaction of IQGAP1 with nephrin (451377)