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Details on Person DSCAM and DCC (Deleted in Colorectal Carcinoma) form a recep...
| Class:Id | Summation:451344 |
|---|---|
| _displayName | DSCAM and DCC (Deleted in Colorectal Carcinoma) form a recep... |
| _timestamp | 2010-11-09 15:36:57 |
| created | [InstanceEdit:451371] Garapati, P V, 2010-01-05 |
| literatureReference | [LiteratureReference:375866] DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1 |
| modified | [InstanceEdit:631249] Garapati, P V, 2010-04-28 [InstanceEdit:1004529] Garapati, P V, 2010-11-09 |
| text | DSCAM and DCC (Deleted in Colorectal Carcinoma) form a receptor complex in commissural axons in the absence of netrin1. They associate through a transmembrane interaction. The functional implication of this interaction is not known, but may allow DCC and DSCAM to contribute to other guidance pathways in a netrin1 independent fashion. It may serve as a way to hold DSCAM and DCC in a resting state, until netrin1 reaches a critical concentration at which both receptors are activated. |
| (summation) | [Reaction:451345] DSCAM binds DCC [Homo sapiens] [Reaction:451360] Dscam binds Dcc [Mus musculus] |
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No pathways have been reviewed or authored by DSCAM and DCC (Deleted in Colorectal Carcinoma) form a recep... (451344)
