Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Diagram of Cell junction organization

Class:IdPathwayDiagram:451081
_displayNameDiagram of Cell junction organization
_timestamp2026-03-02 18:16:59
created[InstanceEdit:451088] Matthews, L, 2009-12-30
height1644
modified[InstanceEdit:1679954] Wu, G, 2011-10-20
[InstanceEdit:1932167] Rothfels, K, 2011-11-02
[InstanceEdit:2193077] Wu, G, 2012-04-11
[InstanceEdit:2430564] Jupe, S, 2012-08-10
[InstanceEdit:3072737] D'Eustachio, P, 2013-02-06
[InstanceEdit:5606986] Matthews, Lisa, 2014-07-08
[InstanceEdit:6784611] Jassal, Bijay, 2015-06-22
[InstanceEdit:8948678] Matthews, Lisa, 2016-11-15
[InstanceEdit:8955888] Jupe, Steve, 2017-01-13
[InstanceEdit:9028777] Gillespie, Marc E, 2017-11-09
[InstanceEdit:9028778] Gillespie, Marc E, 2017-11-09
[InstanceEdit:9605710] Orlic-Milacic, Marija, 2018-04-16
[InstanceEdit:9605711] Orlic-Milacic, Marija, 2018-04-16
[InstanceEdit:9645116] Wu, G, 2019-05-03
[InstanceEdit:9767867] Shamovsky, Veronica, 2022-03-01
[InstanceEdit:9773899] Shamovsky, Veronica, 2022-05-10
[InstanceEdit:9796642] Shamovsky, Veronica, 2022-08-10
[InstanceEdit:9835217] Matthews, Lisa, 2023-05-12
[InstanceEdit:9835375] Orlic-Milacic, Marija, 2023-05-13
[InstanceEdit:9835590] Matthews, Lisa, 2023-05-17
[InstanceEdit:9980365] Orlic-Milacic, Marija, 2026-01-27
[InstanceEdit:9983971] Matthews, Lisa, 2026-03-02
representedPathway[Pathway:446728] Cell junction organization [Homo sapiens]
storedATXML<?xml version="1.0" encoding="UTF-8"?> <Process nextId="601" reactomeDiagramId="451081"> <Properties> <displayName>Diagram of Cell junction organization</displayName> </Properties> <Nodes> <org.gk.render.RenderableComplex id="1" reactomeId="445997" position="1050 1464" bounds="985 1430 131 68" textPosition="984 1434" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Integrin alpha 6:beta 4:Plectin:BP180:Laminin-322 complex</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="2" reactomeId="446066" position="1436 1463" bounds="1371 1429 131 68" textPosition="1370 1433" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>CD151:BP230:BP180:Plectin:Integrin alpha 6 beta 4: Laminin</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="4" reactomeId="446086" position="1631 1482" bounds="1575 1463 113 38" textPosition="1578 1465" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Type II hemidesmosome</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="5" reactomeId="215997" position="296 1470" bounds="245 1447 102 47" textPosition="255 1458" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Integrin alpha6beta4</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableEntity id="6" reactomeId="446069" position="1571 1343" bounds="1529 1329 85 29" textPosition="1530 1332"> <Properties> <displayName>Keratin 5/14</displayName> </Properties> </org.gk.render.RenderableEntity> <org.gk.render.RenderableComplex id="7" reactomeId="446010" position="1270 1468" bounds="1222 1434 97 68" textPosition="1222 1438" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>BP230:BP180:Plectin:integrin alpha 6 beta 4:Laminin 332</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="9" reactomeId="446072" position="1443 1343" bounds="1407 1334 72 19" textPosition="1418 1333"> <Properties> <displayName>CD151</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="10" reactomeId="201575" position="297 1363" bounds="268 1352 58 23" textPosition="279 1352"> <Properties> <displayName>PLEC</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="11" reactomeId="445993" position="758 1478" bounds="694 1452 129 53" textPosition="694 1455" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Integrin alpha6:beta4:Plectin:BP180 complex</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="12" reactomeId="445994" position="567 1479" bounds="529 1454 77 50" textPosition="536 1461"> <Properties> <displayName>COL17A1(1-1497)</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="13" reactomeId="445996" position="449 1469" bounds="384 1450 131 38" textPosition="383 1452" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Integrin alpha 6:beta 4:Plectin complex</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="20" reactomeId="446308" position="1103 1003" bounds="1061 983 85 41" textPosition="1073 988" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>MIGFILIN:VASP</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="21" reactomeId="430323" position="1098 770" bounds="1046 749 105 43" textPosition="1050 756" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Migfilin:Filamin A:F-actin</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="22" reactomeId="430301" position="818 861" bounds="790 850 57 23" textPosition="794 850"> <Properties> <displayName>FBLIM1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableEntitySet id="23" reactomeId="446104" position="501 965" bounds="471 955 60 21" textPosition="479 955"> <Properties> <displayName>PINCH</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="24" reactomeId="446328" position="773 767" bounds="745 756 56 23" textPosition="749 756"> <Properties> <displayName>Filamin</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="25" reactomeId="446032" position="499 1073" bounds="451 1057 97 33" textPosition="461 1056"> <Properties> <displayName>alpha/beta parvin</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableComplex id="26" reactomeId="430295" position="1099 891" bounds="1064 871 70 41" textPosition="1070 876" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>MIG-2:MIGFILIN</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="27" reactomeId="432864" position="293 1005" bounds="274 991 39 29" textPosition="281 994"> <Properties> <displayName>ILK</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="28" reactomeId="446323" position="827 1048" bounds="801 1033 52 30" textPosition="808 1037"> <Properties> <displayName>VASP</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableEntity id="29" reactomeId="201877" position="578 632" bounds="553 621 50 23" textPosition="554 621" /> <org.gk.render.RenderableComplex id="30" reactomeId="432932" position="399 851" bounds="355 823 89 57" textPosition="362 830" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PINCH-ILK-parvin complex</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="31" reactomeId="430275" position="916 935" bounds="887 924 58 23" textPosition="888 924"> <Properties> <displayName>FERMT2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="36" reactomeId="57596" position="141 944" bounds="88 932 106 25" textPosition="119 933"> <Properties> <displayName>ITGB1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="37" reactomeId="446408" position="149 1095" bounds="90 1079 118 33" textPosition="90 1090" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>ILK:Integrin beta-1</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="38" reactomeId="180493" position="149 1173" bounds="125 1162 49 23" textPosition="133 1162"> <Properties> <displayName>PXN</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="39" reactomeId="446326" position="179 1308" bounds="132 1297 94 23" textPosition="133 1298" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PARVA:Paxillin</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="40" reactomeId="432848" position="349 1167" bounds="325 1156 49 23" textPosition="326 1156"> <Properties> <displayName>PARVA</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="44" reactomeId="446035" position="723 1284" bounds="666 1265 115 38" textPosition="680 1267" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>ParvB/Affixin:Alpha-Pix</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="45" reactomeId="354096" position="908 1148" bounds="857 1133 103 31" textPosition="884 1137"> <Properties> <displayName>ACTN1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="46" reactomeId="446302" position="637 824" bounds="575 805 125 38" textPosition="592 807" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Rsu-1:Pinch1 complex</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="47" reactomeId="446016" position="781 1155" bounds="736 1143 91 24" textPosition="758 1144"> <Properties> <displayName>PARVB</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="48" reactomeId="432859" position="608 964" bounds="574 954 68 20" textPosition="587 953"> <Properties> <displayName>LIMS1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="49" reactomeId="446396" position="494 1203" bounds="470 1192 48 23" textPosition="471 1192"> <Properties> <displayName>TESK1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="50" reactomeId="446404" position="409 1313" bounds="365 1302 89 23" textPosition="365 1303" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PARVA:TESK1</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="51" reactomeId="446297" position="687 963" bounds="659 953 56 21" textPosition="668 953"> <Properties> <displayName>RSU1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="52" reactomeId="446335" position="844 1283" bounds="789 1265 111 36" textPosition="801 1265" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PARVB:alpha actinin</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="53" reactomeId="195017" position="654 1171" bounds="618 1160 72 23" textPosition="622 1160"> <Properties> <displayName>ARHGEF6</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="58" reactomeId="420009" position="149 497" bounds="123 486 52 23" textPosition="129 486"> <Properties> <displayName>CRB3</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="59" reactomeId="420006" position="159 232" bounds="92 213 134 38" textPosition="102 215" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>JAM-A:PAR-aPKC complex</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="60" reactomeId="420663" position="179 420" bounds="112 401 134 38" textPosition="122 403" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>CRB3:PALS1:PATJ complex</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="62" reactomeId="420011" position="144 555" bounds="121 544 46 23" textPosition="126 544"> <Properties> <displayName>PATJ</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="64" reactomeId="419976" position="178 366" bounds="115 347 126 38" textPosition="126 349" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Par3:Par6:aPKC complex</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="65" reactomeId="197845" position="146 319" bounds="119 308 55 23" textPosition="127 308"> <Properties> <displayName>F11R</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="66" reactomeId="419969" position="146 610" bounds="117 598 59 24" textPosition="126 599"> <Properties> <displayName>MPP5</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableEntitySet id="70" reactomeId="420583" position="3227 141" bounds="3168 119 119 44" textPosition="3184 116" bgColor="204 255 255"> <Properties> <displayName>Necl-1/Necl-2/Necl-3 homodimer</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableProtein id="71" reactomeId="191735" position="3676 264" bounds="3637 248 78 32" textPosition="3647 253"> <Properties> <displayName>CTNNA1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="72" reactomeId="420594" position="3373 141" bounds="3312 112 122 58" textPosition="3323 120" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Necl-1/Necl-2/Necl-3 trans homodimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableEntitySet id="73" reactomeId="418993" position="3698 206" bounds="3633 187 131 38" textPosition="3632 188"> <Properties> <displayName>Beta-catenin/gamma catenin</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="74" reactomeId="419017" position="577 159" bounds="548 143 58 33" textPosition="555 148"> <Properties> <displayName>Nectin</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableProtein id="75" reactomeId="418342" position="562 339" bounds="530 327 64 24" textPosition="531 328"> <Properties> <displayName>MLLT4-2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="76" reactomeId="418972" position="805 141" bounds="764 121 83 41" textPosition="765 126" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Nectin trans homodimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="77" reactomeId="433726" position="891 475" bounds="843 463 96 25" textPosition="846 466" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Afadin:F-actin</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="78" reactomeId="418976" position="3672 387" bounds="3619 365 106 45" textPosition="3620 374" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Cadherin:Catenin complex</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="79" reactomeId="418999" position="3495 143" bounds="3448 118 95 50" textPosition="3458 118" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Cadherin trans-homodimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="80" reactomeId="419013" position="482 166" bounds="436 139 92 54" textPosition="440 171" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Nectin:afadin</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="81" reactomeId="140648" position="3498 336" bounds="3462 321 73 31" textPosition="3478 325"> <Properties> <displayName>Ca2+</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntitySet id="82" reactomeId="418977" position="3610 143" bounds="3565 128 90 31" textPosition="3580 126"> <Properties> <displayName>Classic Cadherin</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableProtein id="83" reactomeId="418996" position="3660 333" bounds="3621 316 78 34" textPosition="3630 322"> <Properties> <displayName>CTNND1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="84" reactomeId="433730" position="688 156" bounds="626 139 125 35" textPosition="651 138" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Nectin cis-homodimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="92" reactomeId="420601" position="2661 145" bounds="2595 118 132 55" textPosition="2605 137" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Nectin-1:PVRL3 trans heterodimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="93" reactomeId="420575" position="2949 158" bounds="2898 139 103 39" textPosition="2908 142" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Nectin-2 cis homodimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="95" reactomeId="420600" position="1040 163" bounds="1011 153 59 20" textPosition="1025 152"> <Properties> <displayName>PVR</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="96" reactomeId="420607" position="2509 169" bounds="2454 145 110 48" textPosition="2468 157" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Nectin-1 cis homodimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="97" reactomeId="420578" position="2068 144" bounds="1997 118 142 53" textPosition="1998 135" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Nectin-3:Necl-2 trans heterodimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="98" reactomeId="420579" position="931 144" bounds="867 118 129 53" textPosition="877 135" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PRV:PVRL3 trans heterodimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="99" reactomeId="420609" position="2216 143" bounds="2154 117 124 53" textPosition="2157 134" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Nectin-1:Nectin-4 trans heterodimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="100" reactomeId="420590" position="2811 164" bounds="2759 150 104 28" textPosition="2769 156" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PVRL3 dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="101" reactomeId="420587" position="1762 140" bounds="1694 120 136 41" textPosition="1697 125" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Necl-1:Necl-2 trans heterodimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="102" reactomeId="420589" position="1931 127" bounds="1901 112 61 30" textPosition="1906 116"> <Properties> <displayName>CADM1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="104" reactomeId="420585" position="1593 141" bounds="1524 120 139 42" textPosition="1524 126" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Necl-1:Nectin-1 trans heterodimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="105" reactomeId="420577" position="1233 142" bounds="1170 122 126 40" textPosition="1177 126" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Necl-1:Nectin-3 trans heterodimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="106" reactomeId="198169" position="1364 163" bounds="1332 148 65 31" textPosition="1339 152"> <Properties> <displayName>CADM3</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="107" reactomeId="420605" position="3088 141" bounds="3026 118 124 46" textPosition="3034 128" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Nectin-2:PVRL3 transheterodimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="108" reactomeId="420606" position="2360 169" bounds="2305 146 110 46" textPosition="2319 156" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Nectin-4 cis homodimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableEntitySet id="264" reactomeId="419998" position="188 162" bounds="145 148 87 28" textPosition="163 151"> <Properties> <displayName>Claudin</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableComplex id="265" reactomeId="421252" position="354 143" bounds="307 120 95 46" textPosition="310 130" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>claudin trans-homodimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableCompartment id="275" reactomeId="70101" position="1908 817" bounds="144 153 3528 1329" textPosition="2235 782" bgColor="250 240 240" lineColor="255 153 102" insets="155 163 3504 1311"> <Components> <Component id="5" /> <Component id="10" /> <Component id="17" /> <Component id="23" /> <Component id="25" /> <Component id="27" /> <Component id="30" /> <Component id="34" /> <Component id="36" /> <Component id="37" /> <Component id="38" /> <Component id="39" /> <Component id="40" /> <Component id="42" /> <Component id="44" /> <Component id="45" /> <Component id="46" /> <Component id="47" /> <Component id="48" /> <Component id="49" /> <Component id="50" /> <Component id="51" /> <Component id="52" /> <Component id="53" /> <Component id="57" /> <Component id="58" /> <Component id="59" /> <Component id="60" /> <Component id="62" /> <Component id="65" /> <Component id="66" /> <Component id="68" /> <Component id="69" /> <Component id="64" /> <Component id="75" /> <Component id="29" /> <Component id="20" /> <Component id="21" /> <Component id="22" /> <Component id="24" /> <Component id="26" /> <Component id="28" /> <Component id="31" /> <Component id="32" /> <Component id="33" /> <Component id="35" /> <Component id="77" /> <Component id="87" /> <Component id="95" /> <Component id="408" /> <Component id="409" /> <Component id="410" /> <Component id="111" /> <Component id="116" /> <Component id="106" /> <Component id="88" /> <Component id="91" /> <Component id="110" /> <Component id="112" /> <Component id="113" /> <Component id="109" /> <Component id="412" /> <Component id="558" /> <Component id="557" /> <Component id="560" /> <Component id="80" /> <Component id="85" /> <Component id="89" /> <Component id="93" /> <Component id="100" /> <Component id="579" /> <Component id="580" /> <Component id="581" /> <Component id="1" /> <Component id="2" /> <Component id="6" /> <Component id="7" /> <Component id="9" /> <Component id="11" /> <Component id="13" /> <Component id="14" /> <Component id="16" /> <Component id="18" /> <Component id="19" /> <Component id="561" /> <Component id="81" /> <Component id="86" /> <Component id="71" /> <Component id="73" /> <Component id="83" /> <Component id="90" /> <Component id="78" /> <Component id="426" /> <Component id="428" /> <Component id="55" /> <Component id="41" /> <Component id="54" /> <Component id="56" /> <Component id="74" /> <Component id="96" /> <Component id="108" /> <Component id="263" /> <Component id="84" /> <Component id="264" /> <Component id="4" /> <Component id="12" /> <Component id="405" /> <Component id="582" /> <Component id="583" /> <Component id="585" /> <Component id="586" /> <Component id="587" /> <Component id="588" /> <Component id="589" /> </Components> </org.gk.render.RenderableCompartment> <org.gk.render.RenderableCompartment id="276" reactomeId="70101" position="1906 84" bounds="133 39 3546 91" textPosition="2220 64" bgColor="250 240 240" lineColor="255 153 102" insets="144 51 3525 68"> <Properties> <displayName>cytosol</displayName> </Properties> <Components> <Component id="92" /> <Component id="99" /> <Component id="97" /> <Component id="105" /> <Component id="414" /> <Component id="72" /> <Component id="555" /> <Component id="98" /> <Component id="102" /> <Component id="70" /> <Component id="76" /> <Component id="107" /> <Component id="79" /> <Component id="104" /> <Component id="101" /> <Component id="265" /> <Component id="82" /> </Components> </org.gk.render.RenderableCompartment> <org.gk.render.RenderableEntitySet id="405" reactomeId="447012" position="1177 1485" bounds="1152 1475 50 21" textPosition="1154 1475"> <Properties> <displayName>BP230</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableComplex id="411" reactomeId="216001" position="706 1621" bounds="662 1606 89 30" textPosition="665 1614" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Laminin-332</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="412" reactomeId="449762" position="1120 163" bounds="1097 152 46 22" textPosition="1097 152"> <Properties> <displayName>PVRL3</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="414" reactomeId="3008842" position="1371 122" bounds="1348 111 46 22" textPosition="1348 111"> <Properties> <displayName>PVRL1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableEntity id="426" reactomeId="196015" position="3666 439" bounds="3642 428 49 22" textPosition="3642 428"> <Properties> <displayName>F-actin</displayName> </Properties> </org.gk.render.RenderableEntity> <org.gk.render.RenderableProtein id="427" reactomeId="5692435" position="3744 464" bounds="3727 453 35 22" textPosition="3727 453"> <Properties> <displayName>ANG</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="428" reactomeId="5692424" position="3667 523" bounds="3628 512 79 22" textPosition="3628 512" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>F-actin:ANG</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="557" reactomeId="3006482" position="3670 571" bounds="3618 560 105 22" textPosition="3625 560"> <Properties> <displayName>SDK1(?-2213)</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="558" reactomeId="373699" position="3676 674" bounds="3615 656 122 36" textPosition="3619 656" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Trans-homophilic SDK1 dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="560" reactomeId="3006484" position="3671 718" bounds="3645 707 52 22" textPosition="3651 707"> <Properties> <displayName>SDK2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="561" reactomeId="373698" position="3672 822" bounds="3608 803 129 39" textPosition="3615 806" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Trans-homophilic SDK2 dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="579" reactomeId="205188" position="145 666" bounds="92 655 106 23" textPosition="102 656" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>TYRO3 dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="580" reactomeId="202768" position="171 735" bounds="114 702 114 66" textPosition="121 717"> <Properties> <displayName>11xCbxE-GAS6(39-678)</displayName> </Properties> <NodeAttachments> <org.gk.render.RenderableFeature relativeX="0.15350877192982457" relativeY="0.0" label="CA" trackId="0" reactomeId="163832" /> <org.gk.render.RenderableFeature relativeX="0.3201754385964912" relativeY="0.0" label="CA" trackId="0" reactomeId="163811" /> <org.gk.render.RenderableFeature relativeX="0.4868421052631579" relativeY="0.0" label="CA" trackId="0" reactomeId="163830" /> <org.gk.render.RenderableFeature relativeX="0.6535087719298246" relativeY="0.0" label="CA" trackId="0" reactomeId="163796" /> <org.gk.render.RenderableFeature relativeX="0.8201754385964912" relativeY="0.0" label="CA" trackId="0" reactomeId="163803" /> <org.gk.render.RenderableFeature relativeX="1.0" relativeY="0.24242424242424243" label="CA" trackId="0" reactomeId="163806" /> <org.gk.render.RenderableFeature relativeX="1.0" relativeY="0.48484848484848486" label="CA" trackId="0" reactomeId="163828" /> <org.gk.render.RenderableFeature relativeX="1.0" relativeY="0.7272727272727273" label="CA" trackId="0" reactomeId="163826" /> <org.gk.render.RenderableFeature relativeX="0.8464912280701754" relativeY="1.0" label="CA" trackId="0" reactomeId="163794" /> <org.gk.render.RenderableFeature relativeX="0.6798245614035088" relativeY="1.0" label="CA" trackId="0" reactomeId="163807" /> <org.gk.render.RenderableFeature relativeX="0.5131578947368421" relativeY="1.0" label="CA" trackId="0" reactomeId="163797" /> </NodeAttachments> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="581" reactomeId="205291" position="156 811" bounds="92 786 129 50" textPosition="91 800" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Sky : Gas6/Protein-s complex</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="582" reactomeId="9705682" position="316 464" bounds="259 453 115 23" textPosition="259 454" bgColor="204 255 255" lineColor="255 0 0" isForDisease="true" hideComponents="true"> <Properties> <displayName>MMP5:E pentamer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.ProcessNode id="583" reactomeId="9705683" position="489 464" bounds="420 437 139 55" textPosition="427 442" lineColor="255 0 0" isForDisease="true"> <Properties> <displayName>SARS-CoV-2-host interactions</displayName> </Properties> </org.gk.render.ProcessNode> <org.gk.render.ProcessNode id="586" reactomeId="9759476" position="3500 504" bounds="3419 460 163 88" textPosition="3420 482"> <Properties> <displayName>Regulation of Homotypic Cell-Cell Adhesion</displayName> </Properties> </org.gk.render.ProcessNode> <org.gk.render.ProcessNode id="588" reactomeId="9958825" position="3339 328" bounds="3257 293 165 71" textPosition="3264 306"> <Properties> <displayName>Activation of STAT3 by cadherin engagement</displayName> </Properties> </org.gk.render.ProcessNode> </Nodes> <Edges> <org.gk.render.RenderableReaction id="14" reactomeId="446083" points="1375 1362, 1393 1393, 1415 1426" position="1393 1393" lineWidth="1.0"> <Inputs> <Input id="7" points="1303 1431" /> <Input id="9" points="1409 1356" /> </Inputs> <Outputs> <Output id="2" /> </Outputs> <Properties> <displayName>CD151 interacts with BP180 and the integrin alpha 6 subunit</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="15" reactomeId="446089" points="910 1543, 961 1518, 993 1501" position="961 1518" lineWidth="1.0"> <Inputs> <Input id="411" points="745 1603" /> <Input id="11" points="819 1508" /> </Inputs> <Outputs> <Output id="1" /> </Outputs> <Properties> <displayName>BP180 interacts extracellularly with Laminin 332</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="16" reactomeId="446077" points="1549 1418, 1573 1436, 1607 1460" position="1573 1436" lineWidth="1.0"> <Inputs> <Input id="6" points="1566 1361" /> <Input id="2" points="1505 1436" /> </Inputs> <Outputs> <Output id="4" /> </Outputs> <Properties> <displayName>BP230 interacts with keretin K5/K14</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="17" reactomeId="432909" points="364 1399, 395 1408, 432 1447" position="395 1408" lineWidth="1.0"> <Inputs> <Input id="5" points="318 1444" /> <Input id="10" points="318 1378" /> </Inputs> <Outputs> <Output id="13" /> </Outputs> <Properties> <displayName>Interaction of Plectin with Integrin beta 4</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="18" reactomeId="432952" points="546 1404, 629 1408, 709 1449" position="629 1408" lineWidth="1.0"> <Inputs> <Input id="12" points="560 1451" /> <Input id="13" points="477 1447" /> </Inputs> <Outputs> <Output id="11" /> </Outputs> <Properties> <displayName>BP180 interacts intracellularly with plectin and integrin beta4</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="19" reactomeId="432956" points="1154 1416, 1190 1429, 1219 1444" position="1190 1429" lineWidth="1.0"> <Inputs> <Input id="405" points="1173 1469" /> <Input id="1" points="1119 1433" /> </Inputs> <Outputs> <Output id="7" /> </Outputs> <Properties> <displayName>BP230 is recruited to the hemidesmosome</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="32" reactomeId="430341" points="996 890, 1031 890, 1061 890" position="1031 890" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="22" points="850 865" /> <Input id="31" points="936 921" /> </Inputs> <Outputs> <Output id="26" /> </Outputs> <Properties> <displayName>Mig-2 recruits Migfilin to the cell-ECM adhesions</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="33" reactomeId="430347" points="895 770, 979 770, 1043 770" position="979 770" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="22" points="827 847" /> <Input id="29" points="606 642" /> <Input id="24" points="807 767" /> </Inputs> <Outputs> <Output id="21" /> </Outputs> <Properties> <displayName>MigFilin associates with Filamin and F-actin</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="34" reactomeId="446391" points="431 957, 419 918, 407 883" position="419 918" lineWidth="1.0"> <Inputs> <Input id="27" points="316 998" /> <Input id="23" points="465 961" /> <Input id="25" points="489 1051" /> </Inputs> <Outputs> <Output id="30" /> </Outputs> <Properties> <displayName>Formation of the PINCH-ILK-parvin complex</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="35" reactomeId="446364" points="891 998, 961 999, 1058 1001" position="961 999" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="22" points="824 876" /> <Input id="28" points="846 1030" /> </Inputs> <Outputs> <Output id="20" /> </Outputs> <Properties> <displayName>Migfilin interacts with VASP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="41" reactomeId="446322" points="228 1223, 207 1257, 185 1294" position="207 1257" lineWidth="1.0"> <Inputs> <Input id="38" points="167 1188" /> <Input id="40" points="322 1178" /> </Inputs> <Outputs> <Output id="39" /> </Outputs> <Properties> <displayName>PARVA associates with Paxillin</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="42" reactomeId="432897" points="231 1002, 195 1043, 163 1076" position="195 1043" lineWidth="1.0"> <Inputs> <Input id="36" points="160 960" /> <Input id="27" points="271 1004" /> </Inputs> <Outputs> <Output id="37" /> </Outputs> <Properties> <displayName>ILK interacts with beta-1 integrin</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="54" reactomeId="430308" points="842 1193, 843 1232, 843 1262" position="843 1232" lineWidth="1.0"> <Inputs> <Input id="45" points="885 1167" /> <Input id="47" points="800 1170" /> </Inputs> <Outputs> <Output id="52" /> </Outputs> <Properties> <displayName>PARVB interacts with Alpha-actinin</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="55" reactomeId="432946" points="723 1190, 723 1222, 723 1262" position="723 1222" lineWidth="1.0"> <Inputs> <Input id="53" points="693 1180" /> <Input id="47" points="761 1170" /> </Inputs> <Outputs> <Output id="44" /> </Outputs> <Properties> <displayName>PARVB/Affixin interacts with alpha PIX</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="56" reactomeId="446372" points="407 1218, 407 1250, 408 1299" position="407 1250" lineWidth="1.0"> <Inputs> <Input id="49" points="467 1207" /> <Input id="40" points="362 1182" /> </Inputs> <Outputs> <Output id="50" /> </Outputs> <Properties> <displayName>Association of PARVA with TESK1</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="57" reactomeId="430311" points="636 928, 635 891, 636 846" position="635 891" lineWidth="1.0"> <Inputs> <Input id="51" points="671 950" /> <Input id="48" points="615 951" /> </Inputs> <Outputs> <Output id="46" /> </Outputs> <Properties> <displayName>Rsu-1 interacts with Pinch1</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="68" reactomeId="420661" points="225 497, 225 465, 198 442" position="225 465" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="58" points="178 497" /> <Input id="62" points="160 541" /> <Input id="66" points="154 595" /> </Inputs> <Outputs> <Output id="60" /> </Outputs> <Inhibitors> <Inhibitor id="582" points="256 464" /> </Inhibitors> <Properties> <displayName>Crumbs forms a ternary complex with Pals1 and PATJ at tight junctions</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="69" reactomeId="419981" points="203 307, 199 281, 174 254" position="199 281" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="64" points="186 344" /> <Input id="65" points="177 313" /> </Inputs> <Outputs> <Output id="59" /> </Outputs> <Properties> <displayName>Recruitment of PAR-3:PAR-6:aPKC complex to tight junctions</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="85" reactomeId="419003" points="554 213, 527 213, 507 196" position="527 213" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="74" points="569 182" /> <Input id="75" points="564 324, 583 221" /> </Inputs> <Outputs> <Output id="80" /> </Outputs> <Properties> <displayName>Interaction of Nectins with Afadin</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="86" reactomeId="419001" points="3526 241, 3514 199, 3503 171" position="3514 199" lineWidth="1.0"> <Inputs> <Input id="81" stoichiometry="2" points="3502 318" /> <Input id="82" stoichiometry="2" points="3596 165" /> </Inputs> <Outputs> <Output id="79" /> </Outputs> <Properties> <displayName>Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="87" reactomeId="433725" points="687 475, 761 473, 840 474" position="761 473" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="75" points="573 354" /> <Input id="29" points="585 618" /> </Inputs> <Outputs> <Output id="77" /> </Outputs> <Properties> <displayName>Interaction of Afadin with F-actin</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="88" reactomeId="420592" points="3251 169, 3337 239, 3362 173" position="3337 239" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="70" stoichiometry="2" /> </Inputs> <Outputs> <Output id="72" /> </Outputs> <Properties> <displayName>Transhomodimerization of Nectin-like (Necl) proteins</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="89" reactomeId="433711" points="599 182, 674 229, 684 177" position="674 229" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="74" stoichiometry="2" /> </Inputs> <Outputs> <Output id="84" /> </Outputs> <Properties> <displayName>Cis-homodimerization of nectins</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="90" reactomeId="419002" points="3596 246, 3583 386, 3616 386" position="3583 386" lineWidth="1.0"> <Inputs> <Input id="73" points="3649 231" /> <Input id="82" points="3607 165" /> <Input id="83" points="3647 313" /> <Input id="71" points="3634 255" /> </Inputs> <Outputs> <Output id="78" /> </Outputs> <Properties> <displayName>Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="91" reactomeId="419011" points="711 177, 770 218, 795 165" position="770 218" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="84" stoichiometry="2" /> </Inputs> <Outputs> <Output id="76" /> </Outputs> <Properties> <displayName>Transhomodimerization of Nectins</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="109" reactomeId="420591" points="2922 227, 3039 222, 3074 167" position="3039 222" lineWidth="1.0"> <Inputs> <Input id="93" points="2941 181" /> <Input id="100" points="2835 181" /> </Inputs> <Outputs> <Output id="107" /> </Outputs> <Properties> <displayName>Nectin-2:Nectin 3 trans heterodimer interaction</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="110" reactomeId="420595" points="1885 253, 1967 199, 2019 174" position="1967 199" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="412" points="1128 177, 1192 262" /> <Input id="102" points="1925 145" /> </Inputs> <Outputs> <Output id="97" /> </Outputs> <Properties> <displayName>Necl-2:Nectin 3 trans heterodimer interaction</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="111" reactomeId="420598" points="2380 249, 2323 228, 2249 173" position="2323 228" lineWidth="1.0"> <Inputs> <Input id="96" points="2470 196" /> <Input id="108" points="2365 195" /> </Inputs> <Outputs> <Output id="99" /> </Outputs> <Properties> <displayName>Nectin-1:Nectin-4 trans heterodimer formation</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="112" reactomeId="420580" points="2680 248, 2672 206, 2665 176" position="2672 206" lineWidth="1.0"> <Inputs> <Input id="96" points="2560 196" /> <Input id="100" points="2789 181" /> </Inputs> <Outputs> <Output id="92" /> </Outputs> <Properties> <displayName>Nectin-1:PVRL3 trans heterodimer formation</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="113" reactomeId="420584" points="1276 225, 1251 201, 1239 165" position="1251 201" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="106" points="1342 182" /> <Input id="412" points="1146 172" /> </Inputs> <Outputs> <Output id="105" /> </Outputs> <Properties> <displayName>Necl-1:Nectin 3 trans heterodimer interaction</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="114" reactomeId="420582" points="1470 141, 1498 141, 1521 141" position="1498 141" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="106" points="1400 156" /> <Input id="414" points="1397 126" /> </Inputs> <Outputs> <Output id="104" /> </Outputs> <Properties> <displayName>Necl-1:Nectin-1 trans heterodimer interaction</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="116" reactomeId="420586" points="1810 228, 1789 200, 1771 164" position="1789 200" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="106" points="1400 167" /> <Input id="102" points="1913 145" /> </Inputs> <Outputs> <Output id="101" /> </Outputs> <Properties> <displayName>Necl-1:Necl-2 trans heterodimer interaction</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="263" reactomeId="420019" points="238 174, 283 189, 318 169" position="283 189" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="264" stoichiometry="2" /> </Inputs> <Outputs> <Output id="265" /> </Outputs> <Properties> <displayName>Claudins create paired strands through homophilic and heterophilic cis and trans interactions</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="408" points="571 964, 537 964" position="554 964" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="48" /> </Inputs> <Outputs> <Output id="23" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="409" points="368 1153, 471 1096" position="419 1124" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="40" /> </Inputs> <Outputs> <Output id="25" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="410" points="741 1140, 554 1086" position="647 1113" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="47" /> </Inputs> <Outputs> <Output id="25" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="425" reactomeId="5692437" points="3693 479, 3692 480, 3673 509" position="3692 480" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="426" points="3673 453" /> <Input id="427" points="3724 469" /> </Inputs> <Outputs> <Output id="428" /> </Outputs> <Properties> <displayName>ANG binds F-actin</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="555" reactomeId="420593" points="1029 102, 995 102, 971 115" position="995 102" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="95" points="1038 150" /> <Input id="412" points="1103 149" /> </Inputs> <Outputs> <Output id="98" /> </Outputs> <Properties> <displayName>PVR:PVRL3 trans heterodimer interaction</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="556" reactomeId="373745" points="3677 585, 3708 624, 3687 653" position="3708 624" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="557" stoichiometry="2" /> </Inputs> <Outputs> <Output id="558" /> </Outputs> <Properties> <displayName>SDK1 homophillic interaction</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="559" reactomeId="373741" points="3677 732, 3701 767, 3682 800" position="3701 767" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="560" stoichiometry="2" /> </Inputs> <Outputs> <Output id="561" /> </Outputs> <Properties> <displayName>SDK2 homophillic interaction</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="578" reactomeId="205224" points="92 701, 92 769, 117 783" position="92 769" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="579" points="127 681" /> <Input id="580" points="111 710" /> </Inputs> <Outputs> <Output id="581" /> </Outputs> <Properties> <displayName>Interaction of TYRO3 and GAS6</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableInteraction id="585" interactionType="Activate" points="417 462, 377 462" position="397 462" lineWidth="2.0"> <Inputs> <Input id="583" /> </Inputs> <Outputs> <Output id="582" /> </Outputs> </org.gk.render.RenderableInteraction> <org.gk.render.RenderableInteraction id="587" interactionType="Activate" points="3513 457, 3605 165" position="3559 311" lineWidth="2.0"> <Inputs> <Input id="586" /> </Inputs> <Outputs> <Output id="82" /> </Outputs> </org.gk.render.RenderableInteraction> <org.gk.render.RenderableInteraction id="589" interactionType="Activate" points="3473 171, 3369 290" position="3421 230" lineWidth="2.0"> <Inputs> <Input id="79" /> </Inputs> <Outputs> <Output id="588" /> </Outputs> </org.gk.render.RenderableInteraction> </Edges> <Pathways /> </Process>
width3772
[Change default viewing format]
No pathways have been reviewed or authored by Diagram of Cell junction organization (451081)
Follow Reactome