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Details on Person Diagram of Degradation of beta-catenin by the destruction complex, APC truncation mutants are not K63 polyubiquitinated, APC truncation mutants have impaired AXIN binding, Deletions in the AXIN1 gene destabilize the destruction complex, AXIN missense mutants destabilize the destruction complex, Deletions in the AMER1 gene destabilize the destruction complex, Truncations of AMER1 destabilize the destruction complex, CTNNB1 S45 mutants aren't phosphorylated, CTNNB1 T41 mutants aren't phosphorylated, CTNNB1 S37 mutants aren't phosphorylated, CTNNB1 S33 mutants aren't phosphorylated, Signaling by GSK3beta mutants, Signaling by TCF7L2 mutants, and Stabilization of CTNNB1 ubiquitination mutants
| Class:Id | PathwayDiagram:451075 |
|---|---|
| _displayName | Diagram of Degradation of beta-catenin by the destruction complex, APC truncation mutants are not K63 polyubiquitinated, APC truncation mutants have impaired AXIN binding, Deletions in the AXIN1 gene destabilize the destruction complex, AXIN missense mutants destabilize the destruction complex, Deletions in the AMER1 gene destabilize the destruction complex, Truncations of AMER1 destabilize the destruction complex, CTNNB1 S45 mutants aren't phosphorylated, CTNNB1 T41 mutants aren't phosphorylated, CTNNB1 S37 mutants aren't phosphorylated, CTNNB1 S33 mutants aren't phosphorylated, Signaling by GSK3beta mutants, Signaling by TCF7L2 mutants, and Stabilization of CTNNB1 ubiquitination mutants |
| _timestamp | 2023-03-15 11:39:38 |
| created | [InstanceEdit:451078] Matthews, L, 2009-12-30 |
| height | 1488 |
| modified | [InstanceEdit:1457540] Jupe, S, 2011-07-20 [InstanceEdit:1458947] Rothfels, K, 2011-07-22 [InstanceEdit:1504208] Rothfels, K, 2011-08-23 [InstanceEdit:1505516] Rothfels, K, 2011-08-23 [InstanceEdit:2130662] Rothfels, K, 2012-02-21 [InstanceEdit:2193078] Wu, G, 2012-04-11 [InstanceEdit:3050077] Jupe, S, 2013-02-06 [InstanceEdit:3238079] Rothfels, K, 2013-03-27 [InstanceEdit:3305855] Rothfels, K, 2013-04-24 [InstanceEdit:3322442] Rothfels, K, 2013-05-03 [InstanceEdit:3364051] Rothfels, K, 2013-05-13 [InstanceEdit:3601591] Rothfels, K, 2013-05-22 [InstanceEdit:4416746] Rothfels, K, 2013-08-26 [InstanceEdit:4641274] Rothfels, K, 2013-09-27 [InstanceEdit:4649037] Rothfels, K, 2013-09-30 [InstanceEdit:4658500] Rothfels, K, 2013-10-04 [InstanceEdit:4791283] Rothfels, K, 2013-10-28 [InstanceEdit:4827391] Rothfels, K, 2013-10-29 [InstanceEdit:4829345] Rothfels, K, 2013-10-29 [InstanceEdit:4831309] Rothfels, K, 2013-10-29 [InstanceEdit:4833272] Rothfels, K, 2013-10-29 [InstanceEdit:4837328] Rothfels, K, 2013-10-30 [InstanceEdit:4839725] Rothfels, K, 2013-11-01 [InstanceEdit:4839752] Rothfels, K, 2013-11-02 [InstanceEdit:5229364] Rothfels, K, 2014-01-17 [InstanceEdit:5239127] Rothfels, K, 2014-01-17 [InstanceEdit:5246706] Rothfels, K, 2014-01-22 [InstanceEdit:5251597] Rothfels, K, 2014-02-04 [InstanceEdit:5334061] Rothfels, K, 2014-02-21 [InstanceEdit:5339731] Rothfels, K, 2014-03-07 [InstanceEdit:5340169] Rothfels, K, 2014-03-11 [InstanceEdit:5358755] Rothfels, Karen, 2014-04-03 [InstanceEdit:5358756] Rothfels, Karen, 2014-04-03 [InstanceEdit:5358767] Rothfels, Karen, 2014-04-03 [InstanceEdit:5358785] Rothfels, Karen, 2014-04-03 [InstanceEdit:5397973] Rothfels, Karen, 2014-05-01 [InstanceEdit:5406213] Rothfels, Karen, 2014-05-01 [InstanceEdit:5433113] Rothfels, Karen, 2014-05-12 [InstanceEdit:5475174] Rothfels, Karen, 2014-05-16 [InstanceEdit:5475177] Rothfels, Karen, 2014-05-16 [InstanceEdit:5622033] Rothfels, Karen, 2014-09-08 [InstanceEdit:5656306] Rothfels, Karen, 2014-12-11 [InstanceEdit:6782938] Rothfels, Karen, 2015-06-09 [InstanceEdit:8855180] Wu, G, 2016-02-02 [InstanceEdit:8942297] Rothfels, Karen, 2016-10-11 [InstanceEdit:8942383] Rothfels, Karen, 2016-10-13 [InstanceEdit:8943873] Rothfels, Karen, 2016-10-31 [InstanceEdit:8943882] Rothfels, Karen, 2016-10-31 [InstanceEdit:8943888] Rothfels, Karen, 2016-10-31 [InstanceEdit:8944377] Rothfels, Karen, 2016-11-03 [InstanceEdit:8981439] Rothfels, Karen, 2017-03-08 [InstanceEdit:8981476] Rothfels, Karen, 2017-03-08 [InstanceEdit:9645116] Wu, G, 2019-05-03 [InstanceEdit:9663946] Rothfels, Karen, 2019-10-18 [InstanceEdit:9666669] Rothfels, Karen, 2019-11-05 [InstanceEdit:9705362] Rothfels, Karen, 2020-10-23 [InstanceEdit:9705363] Rothfels, Karen, 2020-10-23 [InstanceEdit:9705381] Rothfels, Karen, 2020-10-23 [InstanceEdit:9752973] Rothfels, Karen, 2021-09-02 [InstanceEdit:9753812] Rothfels, Karen, 2021-09-13 [InstanceEdit:9753814] Rothfels, Karen, 2021-09-13 [InstanceEdit:9830823] Rothfels, Karen, 2023-03-15 |
| representedPathway | [Pathway:195253] Degradation of beta-catenin by the destruction complex [Homo sapiens] [Pathway:5467333] APC truncation mutants are not K63 polyubiquitinated [Homo sapiens] [Pathway:5467337] APC truncation mutants have impaired AXIN binding [Homo sapiens] [Pathway:5467345] Deletions in the AXIN1 gene destabilize the destruction complex [Homo sapiens] [Pathway:5467340] AXIN missense mutants destabilize the destruction complex [Homo sapiens] [Pathway:5467343] Deletions in the AMER1 gene destabilize the destruction complex [Homo sapiens] [Pathway:5467348] Truncations of AMER1 destabilize the destruction complex [Homo sapiens] [Pathway:5358751] CTNNB1 S45 mutants aren't phosphorylated [Homo sapiens] [Pathway:5358752] CTNNB1 T41 mutants aren't phosphorylated [Homo sapiens] [Pathway:5358749] CTNNB1 S37 mutants aren't phosphorylated [Homo sapiens] [Pathway:5358747] CTNNB1 S33 mutants aren't phosphorylated [Homo sapiens] [Pathway:5339716] Signaling by GSK3beta mutants [Homo sapiens] [Pathway:5339700] Signaling by TCF7L2 mutants [Homo sapiens] [Pathway:9666656] Stabilization of CTNNB1 ubiquitination mutants [Homo sapiens] |
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<org.gk.render.RenderableReaction id="2812" reactomeId="5334050" points="846 851, 876 851, 877 852, 933 850" position="877 852" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="2813" points="801 879" /> <Input id="2814" points="723 850" /> </Inputs> <Outputs> <Output id="2815" /> </Outputs> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2837" reactomeId="4641229" points="731 574, 799 578, 850 579" position="799 578" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="458" stoichiometry="4" /> </Inputs> <Outputs> <Output id="413" /> </Outputs> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2957" reactomeId="8944352" points="757 685, 784 685, 857 684" position="784 685" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1751" points="726 746" /> <Input id="2958" points="665 685" /> </Inputs> <Outputs> <Output id="2960" /> </Outputs> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndEntitySetLink id="2959" points="633 702, 659 829" position="646 765" lineWidth="0.5" lineColor="128 128 128"> <Inputs> <Input id="2958" /> </Inputs> <Outputs> <Output id="2814" /> </Outputs> </org.gk.render.EntitySetAndEntitySetLink> <org.gk.render.RenderableReaction id="2966" reactomeId="8944349" points="962 624, 988 625, 1024 624" position="988 625" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="413" points="923 601" /> <Input id="2960" points="932 656" /> </Inputs> <Outputs> <Output id="2955" /> </Outputs> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2967" reactomeId="6781905" points="322 147, 277 114, 211 97" position="277 114" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="2968" points="252 170" /> <Input id="1754" points="330 145" /> </Inputs> <Outputs> <Output id="2969" /> </Outputs> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2970" reactomeId="9666616" points="222 66, 304 55, 367 64" position="304 55" lineWidth="1.0"> <Inputs> <Input id="2969" /> </Inputs> <Outputs> <Output id="1755" points="564 106" /> <Output id="314" points="660 156" /> <Output id="2968" points="234 166" /> </Outputs> <Catalysts> <Catalyst id="2969" points="222 86, 274 96" /> </Catalysts> </org.gk.render.RenderableReaction> </Edges> <Pathways /> </Process> |
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No pathways have been reviewed or authored by Diagram of Degradation of beta-catenin by the destruction complex, APC truncation mutants are not K63 polyubiquitinated, APC truncation mutants have impaired AXIN binding, Deletions in the AXIN1 gene destabilize the destruction complex, AXIN missense mutants destabilize the destruction complex, Deletions in the AMER1 gene destabilize the destruction complex, Truncations of AMER1 destabilize the destruction complex, CTNNB1 S45 mutants aren't phosphorylated, CTNNB1 T41 mutants aren't phosphorylated, CTNNB1 S37 mutants aren't phosphorylated, CTNNB1 S33 mutants aren't phosphorylated, Signaling by GSK3beta mutants, Signaling by TCF7L2 mutants, and Stabilization of CTNNB1 ubiquitination mutants (451075)
