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Details on Person Kinase-active interleukin-1 receptor-associated kinases promote polyubiquitination and degradation of the Pellino family: direct evidence for PELLINO proteins being ubiquitin-protein isopeptide ligases

Class:IdLiteratureReference:450816
_displayNameKinase-active interleukin-1 receptor-associated kinases promote polyubiquitination and degradation of the Pellino family: direct evidence for PELLINO proteins being ubiquitin-protein isopeptide ligases
_timestamp2009-12-17 18:07:13
author[Person:450817] Butler, MP
[Person:450829] Hanly, JA
[Person:450823] Moynagh, PN
created[InstanceEdit:450821] Jupe, S, 2009-12-17
journalJ Biol Chem
pages29729-37
pubMedIdentifier17675297
titleKinase-active interleukin-1 receptor-associated kinases promote polyubiquitination and degradation of the Pellino family: direct evidence for PELLINO proteins being ubiquitin-protein isopeptide ligases
volume282
year2007
(literatureReference)[Reaction:434089] IRAK2 possibly binds to Pellino proteins [Gallus gallus]
[Reaction:450690] hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 [Homo sapiens]
[Reaction:937034] IRAK1 phosphorylates Pellino [Homo sapiens]
[Reaction:937050] Pellino ubiquitinates hp-IRAK1 [Homo sapiens]
[Reaction:975122] Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
[Homo sapiens]

[Reaction:975139] IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation [Homo sapiens]
[Summation:451689] Interleukin 1 (IL1) signals via Interleukin 1 receptor 1 (IL...
[Summation:940417] Pellino isoforms -1, 2 and 3 have been shown to interact wit...
[Complex:937020] TRAF6:hp-IRAK1:Pellino [plasma membrane] [Homo sapiens]
[Complex:937040] p-Pellino:hp-IRAK1:TRAF6 [plasma membrane] [Homo sapiens]
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