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Details on Person The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1
| Class:Id | LiteratureReference:450692 |
| _displayName | The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1 |
| _timestamp | 2009-12-17 11:05:04 |
| author | [Person:450689] Ordureau, A [Person:169200] Smith, H [Person:450691] Windheim, M [Person:434107] Peggie, M [Person:450688] Carrick, E [Person:76772] Morrice, N [Person:433958] Cohen, P |
| created | [InstanceEdit:450687] Jupe, S, 2009-12-17 |
| journal | Biochem J |
| modified | [InstanceEdit:450693] Jupe, S, 2009-12-17 |
| pages | 43-52 |
| pubMedIdentifier | 17997719 |
| title | The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1 |
| volume | 409 |
| year | 2008 |
| (literatureReference) | [Summation:451689] Interleukin 1 (IL1) signals via Interleukin 1 receptor 1 (IL... [Summation:940396] Both IRAK1 and IRAK4 were shown to phosphorylate Pellino iso... [Summation:940417] Pellino isoforms -1, 2 and 3 have been shown to interact wit... [Summation:975757] Pellino proteins have been implicated as mediators in mammal... [Reaction:450690] hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 [Homo sapiens] [Reaction:451418] Pellino ubiquitinates IRAK1 [Homo sapiens] [Reaction:937034] IRAK1 phosphorylates Pellino [Homo sapiens] [Reaction:937050] Pellino ubiquitinates hp-IRAK1 [Homo sapiens] [Reaction:975122] Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation [Homo sapiens] [Reaction:975139] IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation [Homo sapiens] |
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