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Details on Person TAK1 is activated within the TAK1 complex

Class:Id	BlackBoxEvent:450187
_displayName	TAK1 is activated within the TAK1 complex
_doRelease	TRUE
_timestamp	2017-09-11 14:12:16
authored	[InstanceEdit:744679] Ray, KP, 2010-05-17
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:450189] Jupe, S, 2009-12-16
edited	[InstanceEdit:744683] Jupe, S, 2010-05-17
input	[Complex:450185] hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:450183] TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop
modified	[InstanceEdit:689003] Jupe, S, 2010-05-07 [InstanceEdit:744684] Jupe, S, 2010-05-17 [InstanceEdit:827364] Jupe, S, 2010-05-27 [InstanceEdit:849794] Jupe, S, 2010-06-01 [InstanceEdit:9020703] Jupe, Steve, 2017-09-11 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TAK1 is activated within the TAK1 complex
output	[Complex:450186] hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] [Homo sapiens]
precedingEvent	[Reaction:688985] K63 polyubiquitinated RIP2 associates with the TAK1 complex [Homo sapiens] [Reaction:688137] RIP2 is K63 polyubiquitinated [Homo sapiens]
releaseDate	2010-06-15
reviewed	[InstanceEdit:744680] Pinteaux, E, 2010-05-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104510] R-HSA-450187.3
summation	[Summation:450184] The TAK1 complex consists of Transforming growth factor-beta...
(hasEvent)	[Pathway:9020702] Interleukin-1 signaling [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9782457] Update Tracker - [BlackBoxEvent:450187] TAK1 is activated within the TAK1 complex - v59:[modifyText] [_UpdateTracker:9788304] Update Tracker - [BlackBoxEvent:450187] TAK1 is activated within the TAK1 complex - v43:[modifyText] [_UpdateTracker:9790084] Update Tracker - [BlackBoxEvent:450187] TAK1 is activated within the TAK1 complex - v35:[modifyText]
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No pathways have been reviewed or authored by TAK1 is activated within the TAK1 complex (450187)