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Details on Person TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop

Class:IdLiteratureReference:450183
_displayNameTAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop
_timestamp2009-12-16 17:09:46
author[Person:434648] Kishimoto, K
[Person:158711] Matsumoto, K
[Person:170008] Ninomiya-Tsuji, J
created[InstanceEdit:450189] Jupe, S, 2009-12-16
journalJ Biol Chem
pages7359-64
pubMedIdentifier10702308
titleTAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop
volume275
year2000
(literatureReference)[Summation:450184] The TAK1 complex consists of Transforming growth factor-beta...
[Summation:2685555] Binding of TAB2 and TAB3 to K63-linked polyubiquitin chains ...
[Summation:9014311] TAK1 complex consists of transforming growth factor-beta (TG...
[Summation:9645409] The TAK1 complex consists of transforming growth factor-beta...
[CatalystActivityReference:9643631] protein serine/threonine kinase activity of DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop
[Reaction:177692] Activation of recruited TAK1 within the activated TLR3 complex [Homo sapiens]
[BlackBoxEvent:450187] TAK1 is activated within the TAK1 complex [Homo sapiens]
[BlackBoxEvent:706479] TAK1 is activated [Homo sapiens]
[Reaction:936951] Activation of TAK1 complex bound to activated TLR4 complex [Homo sapiens]
[Reaction:936991] Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 [Homo sapiens]
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