Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Distinct molecular mechanism for initiating TRAF6 signalling

Class:IdLiteratureReference:450151
_displayNameDistinct molecular mechanism for initiating TRAF6 signalling
_timestamp2009-12-16 14:15:55
author[Person:443720] Ye, H
[Person:450166] Arron, JR
[Person:188657] Lamothe, B
[Person:450175] Cirilli, M
[Person:75775] Kobayashi, T
[Person:450154] Shevde, NK
[Person:141862] Segal, D
[Person:450146] Dzivenu, OK
[Person:450168] Vologodskaia, M
[Person:450145] Yim, M
[Person:199431] Du, K
[Person:450148] Singh, S
[Person:450153] Pike, JW
[Person:202501] Darnay, BG
[Person:433934] Choi, Y
[Person:202522] Wu, H
created[InstanceEdit:450149] Jupe, S, 2009-12-16
journalNature
pages443-7
pubMedIdentifier12140561
titleDistinct molecular mechanism for initiating TRAF6 signalling
volume418
year2002
(literatureReference)[Summation:446863] Hyperphosphorylated IRAK1, still within the receptor complex...
[Summation:937037] IRAK-2 has two TRAF6 binding motifs that are responsible for...
[Summation:1237376] In mammals, the response to viral infection is mediated thro...
[Reaction:166363] TRAF6 binds to hp- IRAK1 [Homo sapiens]
[Pathway:937042] IRAK2 mediated activation of TAK1 complex [Homo sapiens]
[Reaction:975111] TRAF6 binds to hp- IRAK1/or p-IRAK2:p-IRAK4:MyD88:activated TLR7/8 or 9 [Homo sapiens]
[Pathway:975163] IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation [Homo sapiens]
[Reaction:975857] TRAF6 binds to hp- IRAK1 or p-IRAK2 [Homo sapiens]
[Reaction:2262777] TRAF6 binds to p-IRAK2 [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by Distinct molecular mechanism for initiating TRAF6 signalling (450151)