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Details on Person IL1R1:IL1:IL1RAP binds MYD88 homodimer

Class:IdReaction:450133
_displayNameIL1R1:IL1:IL1RAP binds MYD88 homodimer
_doReleaseTRUE
_timestamp2017-09-11 14:10:49
authored[InstanceEdit:744679] Ray, KP, 2010-05-17
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:450128] Jupe, S, 2009-12-14
edited[InstanceEdit:744683] Jupe, S, 2010-05-17
input[Complex:445758] IL1R1:IL1:IL1RAP [plasma membrane] [Homo sapiens]
[Complex:193932] MYD88 dimer [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:165868] MyD88: an adapter that recruits IRAK to the IL-1 receptor complex
[LiteratureReference:446653] Mass spectrometric analysis of the endogenous type I interleukin-1 (IL-1) receptor signaling complex formed after IL-1 binding identifies IL-1RAcP, MyD88, and IRAK-4 as the stable components
modified[InstanceEdit:507710] Jupe, S, 2010-02-08
[InstanceEdit:744684] Jupe, S, 2010-05-17
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9020703] Jupe, Steve, 2017-09-11
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameIL1R1:IL1:IL1RAP binds MYD88 homodimer
output[Complex:450120] IL1R1:IL1:IL1RAP:MYD88 dimer [plasma membrane] [Homo sapiens]
releaseDate2010-06-15
reviewed[InstanceEdit:744680] Pinteaux, E, 2010-05-17
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1104685] R-HSA-450133.3
summation[Summation:446640] MYD88 is a cytoplasmic adaptor protein that is recruited to ...
(hasEvent)[Pathway:9020702] Interleukin-1 signaling [Homo sapiens]
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No pathways have been reviewed or authored by IL1R1:IL1:IL1RAP binds MYD88 homodimer (450133)