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Details on Person Jupe, S, 2009-12-14

Class:Id	InstanceEdit:450128
_displayName	Jupe, S, 2009-12-14
_timestamp	2009-12-14 17:39:24
author	[Person:391309] Jupe, Steve
dateTime	2009-12-14 22:38:50
(created)	[LiteratureReference:450115] TRAF6 distinctively mediates MyD88- and IRAK-1-induced activation of NF-kappaB [Summation:450116] MYD88 recruits unphosphorylated, inactive IRAK1 to the IL1 r... [Person:450117] Tanamoto, K [Person:450118] Commane, M [LiteratureReference:450119] IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling [Complex:450120] IL1R1:IL1:IL1RAP:MYD88 dimer [plasma membrane] [Homo sapiens] [Complex:450121] p-2S,S376,T,T209,T387-IRAK1:TRAF6 [cytosol] [Homo sapiens] [LiteratureReference:450122] IL-1-induced NFkappa B and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK) [Person:450123] Rao, NL [Summation:450124] MyD88 and Tollip only bind to non-phosphorylated IRAK1 (Wesc... List all 19 refering instances
(modified)	[Complex:445758] IL1R1:IL1:IL1RAP [plasma membrane] [Homo sapiens] [Complex:446637] IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer [plasma membrane] [Homo sapiens] [Summation:446640] MYD88 is a cytoplasmic adaptor protein that is recruited to ... [Reaction:446648] IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 [Homo sapiens] [Pathway:446652] Interleukin-1 family signaling [Homo sapiens] [Summation:446680] IRAK2 has been implicated in IL1R and TLR signaling by the o... [BlackBoxEvent:446684] IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation [Homo sapiens] [Reaction:446692] IRAK1 binds to MYD88 within the IL1R complex [Homo sapiens] [Reaction:446701] IRAK4-activated IRAK1 autophosphorylates [Homo sapiens] [Summation:446704] A series of sequential phosphorylation events lead to full o... List all 15 refering instances
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No pathways have been reviewed or authored by Jupe, S, 2009-12-14 (450128)