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Details on Person IRAK1: a critical signaling mediator of innate immunity

Class:Id	LiteratureReference:450126
_displayName	IRAK1: a critical signaling mediator of innate immunity
_timestamp	2009-12-14 17:39:23
author	[Person:450130] Gottipati, S [Person:450123] Rao, NL [Person:165889] Fung-Leung, WP
created	[InstanceEdit:450128] Jupe, S, 2009-12-14
journal	Cell Signal
pages	269-76
pubMedIdentifier	17890055
title	IRAK1: a critical signaling mediator of innate immunity
volume	20
year	2008
(literatureReference)	[Summation:450124] MyD88 and Tollip only bind to non-phosphorylated IRAK1 (Wesc... [Summation:940394] Hyperphosphorylated IRAK1 and TRAF6 are thought to dissociat... [Reaction:166091] IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex [Homo sapiens] [Reaction:166362] Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex [Homo sapiens] [Reaction:446894] TRAF6 binding leads to IRAK1:TRAF6 release [Homo sapiens] [Reaction:975100] Dissociation of hp-IRAK1/or IRAK2:TRAF6-oligomer from the p-IRAK4 :oligo-Myd88:activated TLR7/8 or 9 complex [Homo sapiens] [Reaction:975115] IRAK1/or IRAK2 binds to the activated IRAK4 :MyD88:activated TLR 7/8 or 9 [Homo sapiens] [Reaction:975852] IRAK1/or IRAK2 binds to the activated IRAK4 :oligo MyD88:activated TLR5 or 10 complex [Homo sapiens] [Reaction:975879] Dissociation of hp-IRAK1:TRAF6 or IRAK2:TRAF6-oligomer from the activated TLR5 or 10:oligo-Myd88:p-IRAK4 complex [Homo sapiens] [Reaction:2262775] Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex [Homo sapiens]
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No pathways have been reviewed or authored by IRAK1: a critical signaling mediator of innate immunity (450126)