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Details on Person IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination

Class:Id	LiteratureReference:450125
_displayName	IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination
_timestamp	2009-12-14 17:39:23
author	[Person:450132] Keating, SE [Person:450127] Maloney, GM [Person:450134] Moran, EM [Person:450131] Bowie, AG
created	[InstanceEdit:450128] Jupe, S, 2009-12-14
journal	J Biol Chem
pages	33435-43
pubMedIdentifier	17878161
title	IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination
volume	282
year	2007
(literatureReference)	[Complex:2262774] TRAF6:p-IRAK2 :p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] [Homo sapiens] [Reaction:166091] IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex [Homo sapiens] [Reaction:434053] TRAF6 binds to p-IRAK2 complexed with activated TLR [Gallus gallus] [Reaction:532632] TRAF6 binds to p-IRAK2 complexed with activated TLR7 or TLR21 [Gallus gallus] [Reaction:936963] IRAK2 induces TRAF6 oligomerization [Homo sapiens] [Pathway:937042] IRAK2 mediated activation of TAK1 complex [Homo sapiens] [Pathway:975163] IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation [Homo sapiens] [Reaction:975185] IRAK2 induces TRAF6 oligomerization initiated from endosomal compartments [Homo sapiens] [Summation:446680] IRAK2 has been implicated in IL1R and TLR signaling by the o... [Summation:571290] There is little experimental data about mammalian IRAK2 medi... List all 12 refering instances
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No pathways have been reviewed or authored by IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination (450125)