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Details on Person GLUT1 tetramer binds 4xATP

Class:IdReaction:450088
_displayNameGLUT1 tetramer binds 4xATP
_doReleaseTRUE
_timestamp2025-08-14 07:58:45
authored[InstanceEdit:450087] D'Eustachio, P, 2009-12-11
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:450085] D'Eustachio, P, 2009-12-11
edited[InstanceEdit:517475] D'Eustachio, P, 2010-02-18
goBiologicalProcess[GO_BiologicalProcess:396397] regulation of D-glucose transmembrane transport
input[Complex:70400] GLUT1 / SLC2A1 tetramer [plasma membrane] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:450093] Structural basis of GLUT1 inhibition by cytoplasmic ATP
modified[InstanceEdit:450111] D'Eustachio, P, 2009-12-11
[InstanceEdit:532423] D'Eustachio, P, 2010-02-26
[InstanceEdit:532680] D'Eustachio, P, 2010-03-02
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:3228474] D'Eustachio, P, 2013-03-25
[InstanceEdit:5673780] Jassal, Bijay, 2015-02-10
[InstanceEdit:8981528] D'Eustachio, Peter, 2017-03-09
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9963472] Stephan, Ralf, 2025-08-14
nameGLUT1 tetramer binds 4xATP
negativePrecedingEvent[NegativePrecedingEvent:9963447] Futile Cycle: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP
output[Complex:450089] GLUT1:ATP tetramer [plasma membrane] [Homo sapiens]
releaseDate2010-03-16
reverseReaction
reviewed[InstanceEdit:165071] Graves, L, Rush, MG, 0000-00-00 00:00:00
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1104644] R-HSA-450088.4
summation[Summation:450091] Cytosolic ATP reversibly associates with GLUT1. This associa...
(hasEvent)[Pathway:189200] Cellular hexose transport [Homo sapiens]
(precedingEvent)[NegativePrecedingEvent:9963449] Futile Cycle: GLUT1 tetramer binds 4xATP
(reverseReaction)[Reaction:450092] GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP [Homo sapiens]
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