Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit

Class:Id	Reaction:450063
_displayName	Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit
_doRelease	TRUE
_timestamp	2017-12-08 18:19:08
authored	[InstanceEdit:744679] Ray, KP, 2010-05-17
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:450083] Jupe, S, 2009-12-11
edited	[InstanceEdit:924611] Jupe, S, 2010-08-06
input	[Complex:450065] IL2:IL2RA:IL2RB:JAK1 [plasma membrane] [Homo sapiens] [Complex:451911] IL2RG:JAK3 [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:538994] Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor [LiteratureReference:450052] Compensatory energetic mechanisms mediating the assembly of signaling complexes between interleukin-2 and its alpha, beta, and gamma(c) receptors
modified	[InstanceEdit:451894] Jupe, S, 2010-01-14 [InstanceEdit:539015] Jupe, S, 2010-03-09 [InstanceEdit:918253] Jupe, S, 2010-08-02 [InstanceEdit:926764] Jupe, S, 2010-08-06 [InstanceEdit:941875] Jupe, S, 2010-09-06 [InstanceEdit:1168657] Jupe, S, 2011-01-05 [InstanceEdit:1213487] Jupe, S, 2011-02-11 [InstanceEdit:1233244] Jupe, S, 2011-03-17 [InstanceEdit:9020559] Duenas, Corina, 2017-09-07 [InstanceEdit:9032270] Orlic-Milacic, Marija, 2017-12-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit
output	[Complex:450080] IL2:IL2R trimer:JAK1:JAK3 [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:450027] Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta [Homo sapiens] [Reaction:451900] IL2RB binds JAK1 [Homo sapiens] [Reaction:450054] Interleukin-2 receptor alpha binds interleukin-2 [Homo sapiens] [Reaction:451895] IL2RG binds JAK3 [Homo sapiens]
releaseDate	2011-03-15
reviewed	[InstanceEdit:1213492] Villarino, A, 2011-02-11 [InstanceEdit:1233246] Dooms, H, 2011-03-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1224906] R-HSA-450063.4
summation	[Summation:450032] Recruitment of the IL-2R gamma chain forms a very stable qua...
(hasEvent)	[Pathway:9020558] Interleukin-2 signaling [Homo sapiens]
(precedingEvent)	[Reaction:451942] Within the IL-2R complex JAK3 phosphorylates JAK1 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9789725] Update Tracker - [Reaction:450063] Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit - v37:[modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit (450063)