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Details on Person Stomski, FC
| Class:Id | Person:450044 |
| _displayName | Stomski, FC |
| _timestamp | 2009-12-11 16:58:48 |
| created | [InstanceEdit:450083] Jupe, S, 2009-12-11 |
| initial | FC |
| surname | Stomski |
| (author) | [LiteratureReference:450043] Human interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but not high-affinity binding [LiteratureReference:879903] The structural and functional basis of cytokine receptor activation: lessons from the common beta subunit of the granulocyte-macrophage colony-stimulating factor, interleukin-3 (IL-3), and IL-5 receptors [LiteratureReference:879924] Mechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors [LiteratureReference:893513] Identification of a Cys motif in the common beta chain of the interleukin 3, granulocyte-macrophage colony-stimulating factor, and interleukin 5 receptors essential for disulfide-linked receptor heterodimerization and activation of all three receptors [LiteratureReference:913385] The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation [LiteratureReference:913396] Identification of a 14-3-3 binding sequence in the common beta chain of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors that is serine-phosphorylated by GM-CSF [LiteratureReference:913402] The phosphoserine-585-dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-kappaB and induction of bcl-2 [LiteratureReference:914172] Site-specific serine phosphorylation of the IL-3 receptor is required for hemopoietic cell survival |
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No pathways have been reviewed or authored by Stomski, FC (450044)