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Details on Person Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta

Class:Id	Reaction:450027
_displayName	Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta
_doRelease	TRUE
_timestamp	2017-12-08 18:19:08
authored	[InstanceEdit:744679] Ray, KP, 2010-05-17
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:450083] Jupe, S, 2009-12-11
edited	[InstanceEdit:924611] Jupe, S, 2010-08-06
input	[Complex:538993] IL2:IL2RA [plasma membrane] [Homo sapiens] [Complex:451905] IL2RB:JAK1 [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:538994] Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor [LiteratureReference:450052] Compensatory energetic mechanisms mediating the assembly of signaling complexes between interleukin-2 and its alpha, beta, and gamma(c) receptors
modified	[InstanceEdit:451894] Jupe, S, 2010-01-14 [InstanceEdit:539015] Jupe, S, 2010-03-09 [InstanceEdit:918253] Jupe, S, 2010-08-02 [InstanceEdit:926764] Jupe, S, 2010-08-06 [InstanceEdit:941875] Jupe, S, 2010-09-06 [InstanceEdit:1168657] Jupe, S, 2011-01-05 [InstanceEdit:1213487] Jupe, S, 2011-02-11 [InstanceEdit:1233244] Jupe, S, 2011-03-17 [InstanceEdit:9020559] Duenas, Corina, 2017-09-07 [InstanceEdit:9032270] Orlic-Milacic, Marija, 2017-12-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta
output	[Complex:450065] IL2:IL2RA:IL2RB:JAK1 [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:451900] IL2RB binds JAK1 [Homo sapiens] [Reaction:450054] Interleukin-2 receptor alpha binds interleukin-2 [Homo sapiens]
releaseDate	2011-03-15
reviewed	[InstanceEdit:1213492] Villarino, A, 2011-02-11 [InstanceEdit:1233246] Dooms, H, 2011-03-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1225040] R-HSA-450027.4
summation	[Summation:450047] The crystal structure of the assembled IL2:IL2 receptor comp...
(hasEvent)	[Pathway:9020558] Interleukin-2 signaling [Homo sapiens]
(precedingEvent)	[Reaction:450063] Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9789700] Update Tracker - [Reaction:450027] Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta - v37:[modifyText]
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No pathways have been reviewed or authored by Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta (450027)