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Details on Person IL7 binds IL7R:JAK1

Class:IdReaction:449978
_displayNameIL7 binds IL7R:JAK1
_doReleaseTRUE
_timestamp2017-10-16 09:12:50
authored[InstanceEdit:744679] Ray, KP, 2010-05-17
compartment[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:449954] Jupe, S, 2009-12-11
edited[InstanceEdit:1264800] Jupe, S, 2011-05-06
input[EntityWithAccessionedSequence:447209] IL7 [extracellular region] [Homo sapiens]
[Complex:1264843] IL7R:JAK1 [plasma membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:449972] Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily
modified[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:1264814] Jupe, S, 2011-05-06
[InstanceEdit:1295522] Jupe, S, 2011-05-17
[InstanceEdit:1295755] Jupe, S, 2011-05-18
[InstanceEdit:1963544] Jupe, S, 2011-11-03
[InstanceEdit:1963554] Jupe, S, 2011-11-03
[InstanceEdit:6785154] Jupe, Steve, 2015-06-25
[InstanceEdit:8983039] Duenas, Corina, 2017-03-22
[InstanceEdit:9025936] Jupe, Steve, 2017-10-16
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameIL7 binds IL7R:JAK1
output[Complex:449983] IL7:IL7R:JAK1 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2011-12-06
reviewed[InstanceEdit:1963543] Puck, J, 2011-11-03
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2016389] R-HSA-449978.5
summation[Summation:449979] Interleukin-7 receptor alpha chain (IL7R) binds interleukin-...
(hasEvent)[Pathway:1266695] Interleukin-7 signaling [Homo sapiens]
(precedingEvent)[Reaction:449958] IL7:IL7R:JAK1 binds IL2RG:JAK3 [Homo sapiens]
[BlackBoxEvent:8983022] FYN is phosphorylated by IL7:IL7R:JAK1:FYN:LCK [Homo sapiens]
[BlackBoxEvent:8983071] IL7:IL7R:JAK1:FYN:LCK phosphorylates LCK [Homo sapiens]
(updatedInstance)[_UpdateTracker:9780192] Update Tracker - [Reaction:449978] IL7 binds IL7R:JAK1 - v63:[modifyText]
[_UpdateTracker:9781257] Update Tracker - [Reaction:449978] IL7 binds IL7R:JAK1 - v61:[modifyText]
[_UpdateTracker:9784362] Update Tracker - [Reaction:449978] IL7 binds IL7R:JAK1 - v54:[modifyText]
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No pathways have been reviewed or authored by IL7 binds IL7R:JAK1 (449978)