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Details on Person IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2)

Class:Id	Reaction:449976
_displayName	IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2)
_doRelease	TRUE
_timestamp	2017-05-26 10:26:19
authored	[InstanceEdit:449839] Jupe, S, 2009-12-07
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:449954] Jupe, S, 2009-12-11
edited	[InstanceEdit:6788465] Garapati, Phani Vijay, 2015-07-21
input	[Complex:449799] IL11RA:IL11 [plasma membrane] [Homo sapiens] [Complex:1067690] IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:449965] Cloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transduction [LiteratureReference:449969] The human IL-11 receptor requires gp130 for signalling: demonstration by molecular cloning of the receptor
modified	[InstanceEdit:6784209] Garapati, Phani Vijay, 2015-06-18 [InstanceEdit:6784609] Garapati, Phani Vijay, 2015-06-22 [InstanceEdit:6787775] Jupe, Steve, 2015-07-17 [InstanceEdit:6803161] Jupe, Steve, 2015-10-05 [InstanceEdit:6809137] Garapati, Phani Vijay, 2015-11-09 [InstanceEdit:6809167] Garapati, Phani Vijay, 2015-11-09 [InstanceEdit:9007063] Jupe, Steve, 2017-05-26 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) Interleukin-11 receptor alpha:Interleukin-11 binds Interleukin-6 receptor beta
output	[Complex:449948] IL6RA:IL6:IL6RB:JAKs [plasma membrane] [Homo sapiens]
releaseDate	2015-12-15
releaseStatus	NEW
reviewed	[InstanceEdit:6809153] Narazaki, M, Tanaka, M, 2015-11-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6812279] R-HSA-449976.3
summation	[Summation:449963] Interleukin-11 receptor alpha subunit (IL11RA) binds interle...
(hasEvent)	[Pathway:6788467] IL-6-type cytokine receptor ligand interactions [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9780667] Update Tracker - [Reaction:449976] IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) - v62:[modifyText]
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No pathways have been reviewed or authored by IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) (449976)