Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person IL10 dimer binds IL10RA:JAK1

Class:IdReaction:449803
_displayNameIL10 dimer binds IL10RA:JAK1
_doReleaseTRUE
_timestamp2016-11-14 13:49:14
authored[InstanceEdit:6783726] Jupe, Steve, 2015-06-17
compartment[Compartment:984] extracellular region
[Compartment:876] plasma membrane
[Compartment:70101] cytosol
created[InstanceEdit:449839] Jupe, S, 2009-12-07
edited[InstanceEdit:8948388] Jupe, Steve, 2016-11-14
input[Complex:449854] IL10 dimer [extracellular region] [Homo sapiens]
[Complex:6783816] IL10RA:JAK1 [plasma membrane] [Homo sapiens]
[Complex:6783816] IL10RA:JAK1 [plasma membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:449776] Expression cloning and characterization of a human IL-10 receptor
modified[InstanceEdit:449857] Jupe, S, 2009-12-07
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:6783726] Jupe, Steve, 2015-06-17
[InstanceEdit:6783804] Jupe, Steve, 2015-06-17
[InstanceEdit:6784364] Jupe, Steve, 2015-06-19
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:8933245] Jupe, Steve, 2016-08-04
[InstanceEdit:8934460] Jupe, Steve, 2016-08-09
[InstanceEdit:8937645] Jupe, Steve, 2016-09-05
[InstanceEdit:8937646] Jupe, Steve, 2016-09-05
[InstanceEdit:8948394] Jupe, Steve, 2016-11-14
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameIL10 dimer binds IL10RA:JAK1
output[Complex:449802] IL10 dimer:2xIL10RA:JAK1 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2016-12-12
reviewed[InstanceEdit:8937647] Meldal, Birgit, 2016-09-05
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8901000] R-HSA-449803.2
summation[Summation:449775] The IL-10 receptor is composed of at least two subunits, bot...
(hasEvent)[Pathway:6783783] Interleukin-10 signaling [Homo sapiens]
(precedingEvent)[Reaction:449811] IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by IL10 dimer binds IL10RA:JAK1 (449803)