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Details on Person Addition of a third mannose to the N-glycan precursor by Alg2

Class:Id	Reaction:449748
_displayName	Addition of a third mannose to the N-glycan precursor by Alg2
_doRelease	TRUE
_timestamp	2024-05-16 13:58:53
authored	[InstanceEdit:749521] Dall'Olio, GM, 2009-11-10
catalystActivity	[CatalystActivity:449735] alpha-1,6-mannosyltransferase activity of Alg2 [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol [Compartment:5263266] cytoplasmic side of endoplasmic reticulum membrane
created	[InstanceEdit:449736] Jassal, B, 2009-12-07
edited	[InstanceEdit:449736] Jassal, B, 2009-12-07
input	[SimpleEntity:449737] (GlcNAc)2 (Man)2 (PP-Dol)1 [cytoplasmic side of endoplasmic reticulum membrane] [SimpleEntity:162860] GDP-Man [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:449740] In vitro evidence for the dual function of Alg2 and Alg11: essential mannosyltransferases in N-linked glycoprotein biosynthesis [LiteratureReference:449741] Biochemical characterization and membrane topology of Alg2 from Saccharomyces cerevisiae as a bifunctional alpha1,3- and 1,6-mannosyltransferase involved in lipid-linked oligosaccharide biosynthesis
modified	[InstanceEdit:449769] Jassal, B, 2009-12-07 [InstanceEdit:449893] Jassal, B, 2009-12-09 [InstanceEdit:749524] Jassal, B, 2010-05-19 [InstanceEdit:1031641] Jassal, B, 2010-11-18 [InstanceEdit:1031644] Jassal, B, 2010-11-18 [InstanceEdit:1168649] Jassal, B, 2011-01-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9910684] D'Eustachio, Peter, 2024-05-16
name	Addition of a third mannose to the N-glycan precursor by Alg2
output	[SimpleEntity:449243] (GlcNAc)2 (Man)3 (PP-Dol)1 [cytoplasmic side of endoplasmic reticulum membrane] [SimpleEntity:29420] GDP [cytosol]
releaseDate	2010-06-15
reviewed	[InstanceEdit:749519] Gagneux, P, 2010-04-16
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:68322] Saccharomyces cerevisiae
stableIdentifier	[StableIdentifier:1225023] R-SCE-449748.3
summation	[Summation:449707] A third mannose is added to the N-glycan precursor skeleton ...
(inferredFrom)	[Reaction:449718] Addition of a third mannose to the N-glycan precursor by ALG2 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9782568] Update Tracker - [Reaction:449748] Addition of a third mannose to the N-glycan precursor by Alg2 - v59:[modifyText] [_UpdateTracker:9789805] Update Tracker - [Reaction:449748] Addition of a third mannose to the N-glycan precursor by Alg2 - v37:[modifyText]
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