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Details on Person A third mannose is added to the N-glycan precursor by ALG2 u...

Class:IdSummation:449708
_displayNameA third mannose is added to the N-glycan precursor by ALG2 u...
_timestamp2010-05-21 14:20:33
created[InstanceEdit:449736] Jassal, B, 2009-12-07
modified[InstanceEdit:604389] Jassal, B, 2010-04-16
[InstanceEdit:772532] Jassal, B, 2010-05-21
textA third mannose is added to the N-glycan precursor by ALG2 using its alpha1,6-mannosyltransferase activity. This has been demonstrated experimentally in yeast (O'Reilly MK et al, 2006; Kämpf M et al, 2009); the human reaction is inferred by homology. Defects in ALG2 are the cause for CDG1I (Thiel C et al, 2003).
(summation)[Reaction:449718] Addition of a third mannose to the N-glycan precursor by ALG2 [Homo sapiens]
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