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Details on Person Addition of a third glucose to the N-glycan skeleton by Alg10

Class:Id	Reaction:449661
_displayName	Addition of a third glucose to the N-glycan skeleton by Alg10
_doRelease	TRUE
_timestamp	2024-05-16 13:58:51
authored	[InstanceEdit:749521] Dall'Olio, GM, 2009-11-10
catalystActivity	[CatalystActivity:449660] dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity of DIE2 [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:5263265] lumenal side of endoplasmic reticulum membrane
created	[InstanceEdit:449659] Jassal, B, 2009-12-03
edited	[InstanceEdit:449659] Jassal, B, 2009-12-03
input	[SimpleEntity:449638] (Glc)2 (GlcNAc)2 (Man)9 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane] [SimpleEntity:532542] DbGP [lumenal side of endoplasmic reticulum membrane]
isChimeric	FALSE
literatureReference	[LiteratureReference:449657] The ALG10 locus of Saccharomyces cerevisiae encodes the alpha-1,2 glucosyltransferase of the endoplasmic reticulum: the terminal glucose of the lipid-linked oligosaccharide is required for efficient N-linked glycosylation
modified	[InstanceEdit:449663] Jassal, B, 2009-12-03 [InstanceEdit:449769] Jassal, B, 2009-12-07 [InstanceEdit:749524] Jassal, B, 2010-05-19 [InstanceEdit:913606] Jassal, B, 2010-07-19 [InstanceEdit:1031644] Jassal, B, 2010-11-18 [InstanceEdit:1813859] Jassal, B, 2011-10-25 [InstanceEdit:1972365] Jassal, B, 2011-11-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9910684] D'Eustachio, Peter, 2024-05-16
name	Addition of a third glucose to the N-glycan skeleton by Alg10
output	[SimpleEntity:449651] (Glc)3 (GlcNAc)2 (Man)9 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane] [SimpleEntity:449311] DOLP [lumenal side of endoplasmic reticulum membrane]
releaseDate	2010-06-15
reviewed	[InstanceEdit:749519] Gagneux, P, 2010-04-16
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:68322] Saccharomyces cerevisiae
stableIdentifier	[StableIdentifier:2016592] R-SCE-449661.3
summation	[Summation:749523] The last glucose is added to the N-glycan precursor. This re...
(inferredFrom)	[Reaction:446194] Addition of a third glucose to the N-glycan precursor by an ALG10 homologue [Homo sapiens]
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