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Details on Person Addition of the fourth and fifth mannose to the N-glycan precursor skeleton by Alg11

Class:Id	Reaction:449324
_displayName	Addition of the fourth and fifth mannose to the N-glycan precursor skeleton by Alg11
_doRelease	TRUE
_timestamp	2024-05-16 13:58:54
authored	[InstanceEdit:749521] Dall'Olio, GM, 2009-11-10
catalystActivity	[CatalystActivity:449304] alpha-1,2-mannosyltransferase activity of ALG11 [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol [Compartment:5263266] cytoplasmic side of endoplasmic reticulum membrane
created	[InstanceEdit:449318] Jassal, B, 2009-12-02
edited	[InstanceEdit:449318] Jassal, B, 2009-12-02
input	[SimpleEntity:449243] (GlcNAc)2 (Man)3 (PP-Dol)1 [cytoplasmic side of endoplasmic reticulum membrane] [SimpleEntity:162860] GDP-Man [cytosol] [SimpleEntity:162860] GDP-Man [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:449341] The yeast ALG11 gene specifies addition of the terminal alpha 1,2-Man to the Man5GlcNAc2-PP-dolichol N-glycosylation intermediate formed on the cytosolic side of the endoplasmic reticulum
modified	[InstanceEdit:449663] Jassal, B, 2009-12-03 [InstanceEdit:449664] Jassal, B, 2009-12-03 [InstanceEdit:749524] Jassal, B, 2010-05-19 [InstanceEdit:1031644] Jassal, B, 2010-11-18 [InstanceEdit:1227932] Jassal, B, 2011-03-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9910684] D'Eustachio, Peter, 2024-05-16
name	Addition of the fourth and fifth mannose to the N-glycan precursor skeleton by Alg11
output	[SimpleEntity:449332] (GlcNAc)2 (Man)5 (PP-Dol)1 [cytoplasmic side of endoplasmic reticulum membrane] [SimpleEntity:29420] GDP [cytosol] [SimpleEntity:29420] GDP [cytosol]
releaseDate	2010-06-15
reviewed	[InstanceEdit:749519] Gagneux, P, 2010-04-16
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:68322] Saccharomyces cerevisiae
stableIdentifier	[StableIdentifier:1104443] R-SCE-449324.3
summation	[Summation:449248] A fourth and fifth mannose is added to the N-glycan precurso...
(inferredFrom)	[Reaction:446187] ALG11 transfers the fourth and fifth Man to the N-glycan precursor [Homo sapiens]
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