Query author contributions in Reactome
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Details on Person The seventh mannose is added to the N-glycan precursor. This...
| Class:Id | Summation:449285 |
|---|---|
| _displayName | The seventh mannose is added to the N-glycan precursor. This... |
| _timestamp | 2010-07-29 08:25:07 |
| created | [InstanceEdit:449318] Jassal, B, 2009-12-02 |
| modified | [InstanceEdit:449659] Jassal, B, 2009-12-03 [InstanceEdit:449893] Jassal, B, 2009-12-09 [InstanceEdit:604389] Jassal, B, 2010-04-16 [InstanceEdit:916859] Jassal, B, 2010-07-29 |
| text | The seventh mannose is added to the N-glycan precursor. This reaction occurs in the ER lumen and uses dolichyl phosphate D-mannose as the mannose donor with ALG9 mediating the reaction. Defects in ALG9 are the cause of congenital disorder of glycosylation type 1L (CDG1L) (Frank CG et al, 2004; Weinstein M et al, 2005). For many years ALG9 has been thought to be involved in bipolar affective disorder (Baysal BE et al, 2002), but this hypothesis has been proven wrong (Baysal BE et al, 2006). |
| (summation) | [Reaction:446215] ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 [Homo sapiens] |
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No pathways have been reviewed or authored by The seventh mannose is added to the N-glycan precursor. This... (449285)
