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Details on Person G-proteins in the Gi class inhibit adenylate cyclase activit...

Class:IdSummation:449171
_displayNameG-proteins in the Gi class inhibit adenylate cyclase activit...
_timestamp2017-03-21 15:46:22
created[InstanceEdit:449170] Jupe, S, 2009-11-30
literatureReference[LiteratureReference:374954] Inhibition of adenylyl cyclase by Gi alpha
[LiteratureReference:8982636] Mechanism of Galpha i-mediated inhibition of type V adenylyl cyclase
modified[InstanceEdit:425319] Jupe, S, 2009-06-03
[InstanceEdit:8982644] Varusai, Thawfeek, 2017-03-21
textG-proteins in the Gi class inhibit adenylate cyclase activity, decreasing the production of cAMP from ATP, which has many consequences but classically results in decreased activity of Protein Kinase A (PKA). cAMP also activates the cyclic nucleotide-gated ion channels, a process that is particularly important in olfactory cells.
(summation)[Reaction:392206] G alpha (i) inhibits adenylate cyclase [Homo sapiens]
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