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Details on Person CD4 is a receptor for Interleukin-16 (IL16), explaining how ...
| Class:Id | Summation:449099 |
|---|---|
| _displayName | CD4 is a receptor for Interleukin-16 (IL16), explaining how ... |
| _timestamp | 2016-01-27 16:41:15 |
| created | [InstanceEdit:449066] Jupe, S, 2009-11-27 |
| literatureReference | [LiteratureReference:449088] Cutting edge: CD4 is not required for the functional activity of IL-16 [LiteratureReference:449074] Interleukin-16 [LiteratureReference:8854476] lnterleukin-16: the ins and outs of regulating T-cell activation |
| modified | [InstanceEdit:6804717] Jupe, Steve, 2015-10-14 [InstanceEdit:8854506] Jupe, Steve, 2016-01-27 |
| text | CD4 is a receptor for Interleukin-16 (IL16), explaining how IL16 acts as a chemoattractant for a variety of CD4+ immune cells (Cruikshank et al. 2000, Cruikshank & Little 2008). Signaling mediated by CD4 requires the amino acid sequence W345 to S350, located in the proximal end of the D4 domain. CD4 does not appear to require a co-receptor for IL16. Data from CD4 knockout mice suggests that there may be an additional IL16 receptor (Mathy et al. 2000). |
| (summation) | [Reaction:449087] CD4 binds Interleukin-16 [Homo sapiens] |
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No pathways have been reviewed or authored by CD4 is a receptor for Interleukin-16 (IL16), explaining how ... (449099)
