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Details on Person Activation of p38 alpha/beta MAPK

Class:Id	BlackBoxEvent:448951
_displayName	Activation of p38 alpha/beta MAPK
_doRelease	TRUE
_timestamp	2010-12-02 14:34:48
authored	[InstanceEdit:375169] Garapati, P V, 2008-08-11 10:36:48
catalystActivity	[CatalystActivity:448952] MAP kinase kinase activity of p-S207,T211-MAP2K6 [cytosol]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:448956] Garapati, P V, 2009-11-26
edited	[InstanceEdit:375169] Garapati, P V, 2008-08-11 10:36:48
inferredFrom	[BlackBoxEvent:448961] Activation of p38 alpha/beta MAPK [Mus musculus]
input	[Complex:448887] p38 alpha/beta/gamma:ABL1:JLP:CDO complex [plasma membrane] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
modified	[InstanceEdit:448964] Garapati, P V, 2009-11-26 [InstanceEdit:507896] Garapati, P V, 2010-02-09 [InstanceEdit:513000] Garapati, P V, 2010-02-16 [InstanceEdit:741400] Jupe, S, 2010-05-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Activation of p38 alpha/beta MAPK
output	[Complex:448881] pp38 alpha/beta/gamma:ABL1:JLP:CDO complex [plasma membrane] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:448957] Interaction of p38 MAPK with JLP [Homo sapiens] [Reaction:449200] Interaction of ABL1 with CDO complex [Homo sapiens] [Reaction:727819] TAK1 phosphorylates MKK6 [Homo sapiens] [BlackBoxEvent:706479] TAK1 is activated [Homo sapiens]
releaseDate	2010-03-16
reviewed	[InstanceEdit:507894] Krauss, RS, 2010-02-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104591] R-HSA-448951.2
summation	[Summation:448804] p38 alpha/beta MAPK is well established as a promyogenic kin...
(hasEvent)	[Pathway:525793] Myogenesis [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:448958] Nuclear translocation of p38 MAPK [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9789624] Update Tracker - [BlackBoxEvent:448951] Activation of p38 alpha/beta MAPK - v37:[modifyText]
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No pathways have been reviewed or authored by Activation of p38 alpha/beta MAPK (448951)