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Details on Person p38 MAPK plays a fundamental role in the transition of myobl...

Class:IdSummation:448802
_displayNamep38 MAPK plays a fundamental role in the transition of myobl...
_timestamp2010-01-19 09:34:18
created[InstanceEdit:448806] Garapati, P V, 2009-11-26
modified[InstanceEdit:453163] Garapati, P V, 2010-01-19
textp38 MAPK plays a fundamental role in the transition of myoblasts to different myocytes. Activated p38 MAPK phosphorylates E12/E47, a member of the E protein subfamily of bHLH proteins. p38 MAPK in particular phosphorylates Ser140 of E47. Its been observed that phosphorylation of E47 improves its ability to form heterodimers with Myod transcription factor.
(summation)[Reaction:448948] Phosphorylation of E proteins by p38 MAPK [Homo sapiens]
[Reaction:448953] Phosphorylation of E47 by p38 MAPK [Mus musculus]
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