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Query author contributions in Reactome

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Details on Person Interleukin-22 receptor subunit alpha-2 (IL22RA2), also know...

Class:IdSummation:448723
_displayNameInterleukin-22 receptor subunit alpha-2 (IL22RA2), also know...
_timestamp2017-07-04 13:53:48
created[InstanceEdit:448729] Jupe, S, 2009-11-25
literatureReference[LiteratureReference:448430] A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist
[LiteratureReference:8854665] Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22
[LiteratureReference:448721] Cloning and characterization of IL-22 binding protein, a natural antagonist of IL-10-related T cell-derived inducible factor/IL-22
[LiteratureReference:448742] Identification, cloning, and characterization of a novel soluble receptor that binds IL-22 and neutralizes its activity
modified[InstanceEdit:6804715] Jupe, Steve, 2015-10-14
[InstanceEdit:8854660] Jupe, Steve, 2016-01-28
[InstanceEdit:8986392] Duenas, Corina, 2017-04-26
[InstanceEdit:9005490] Duenas, Corina, 2017-05-09
[InstanceEdit:9009145] Duenas, Corina, 2017-06-15
[InstanceEdit:9009474] Duenas, Corina, 2017-06-19
[InstanceEdit:9011699] Duenas, Corina, 2017-07-04
[InstanceEdit:9011704] Duenas, Corina, 2017-07-04
textInterleukin-22 receptor subunit alpha-2 (IL22RA2), also known as Interleukin-22 binding protein (IL22BP), is a soluble receptor that binds Interleukin-22 (IL22) within the extracellular region, preventing IL22 from binding to the functional membrane-associated IL22 receptor (Xu et al. 2001, De Moura et al. 2009, Dumoutier et al. 2001, Kotenko et al. 2001). This may play a regulatory role in inflammation.
(summation)[Reaction:448741] IL22RA2 binds IL22 [Homo sapiens]
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