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Details on Person CASP1(1-404) [cytosol]

Class:IdEntityWithAccessionedSequence:448692
_displayNameCASP1(1-404) [cytosol]
_timestamp2013-05-03 18:44:31
compartment[Compartment:70101] cytosol
created[InstanceEdit:448681] Jupe, S, 2009-11-25
endCoordinate404
modified[InstanceEdit:448729] Jupe, S, 2009-11-25
[InstanceEdit:449665] Jupe, S, 2009-12-03
[InstanceEdit:874110] Jupe, S, 2010-06-10
[InstanceEdit:877366] Jupe, S, 2010-06-14
[InstanceEdit:3322333] Wu, G, 2013-05-03
[InstanceEdit:3322334] Wu, G, 2013-05-03
nameCASP1(1-404)
Procaspase-1
CASP1 propeptide
Caspase-1 propeptide
CASP1
CASP1_HUMAN
referenceEntity[ReferenceGeneProduct:56948] UniProt:P29466 CASP1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1109020] R-HSA-448692.1
startCoordinate1
(activeUnit)[CatalystActivity:9712439] cysteine-type endopeptidase activity of NLRP3 oligomer:MAVS:TRAF3:K63polyUb-PYCARD oligomer:procaspase-1 [mitochondrial outer membrane]
[CatalystActivity:9735709] cysteine-type endopeptidase activity of NLRP3 elicitors:NLRP3 oligomer:PYCARD oligomer:CASP1 [cytosol]
(hasCandidate)[CandidateSet:622416] Long prodomain caspases [cytosol] [Homo sapiens]
(hasComponent)[Complex:874083] IPAF elicitors:NLRC4:Procaspase-1 [cytosol] [Homo sapiens]
[Complex:874100] dsDNA:AIM2 oligomer:ASC:Procaspase-1 [cytosol] [Homo sapiens]
[Complex:877371] MDP:NLRP1:ATP Oligomer:Procaspase-1 [cytosol] [Homo sapiens]
[Complex:925458] NLRP3 elicitors:NLRP3 oligomer:ASC:Procaspase-1 [cytosol] [Homo sapiens]
[Complex:9712414] NLRP3 oligomer:MAVS:TRAF3:K63polyUb-PYCARD oligomer:procaspase-1 [mitochondrial outer membrane] [Homo sapiens]
[Complex:9735700] NLRP3 elicitors:NLRP3 oligomer:PYCARD oligomer:CASP1 [cytosol] [Homo sapiens]
(input)[Reaction:448678] CTSG cleaves CASP1(1-404) [Homo sapiens]
[Reaction:844608] NLRP1 binds procaspase-1 [Homo sapiens]
[Reaction:844612] PYCARD recruits procaspase-1 via CARD [Homo sapiens]
[Reaction:844617] IPAF binds procaspase-1 [Homo sapiens]
[Reaction:844618] dsDNA:AIM2:ASC cluster binds procaspase-1 [Homo sapiens]
[Reaction:9712408] PYCARD oligomer recruits procaspase-1 [Homo sapiens]
(output)[BlackBoxEvent:6798081] TP53 family members stimulate CASP1 expression [Homo sapiens]
(updatedInstance)[_UpdateTracker:9881537] Update Tracker - [EntityWithAccessionedSequence:448692] CASP1(1-404) [cytosol] - v45:[addName]
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No pathways have been reviewed or authored by CASP1(1-404) [cytosol] (448692)