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Details on Person A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

Class:IdLiteratureReference:448676
_displayNameA novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
_timestamp2009-11-25 17:24:37
author[Person:265491] Thornberry, NA
[Person:265463] Bull, HG
[Person:448683] Calaycay, JR
[Person:265465] Chapman, KT
[Person:388997] Howard, AD
[Person:448693] Kostura, MJ
[Person:448690] Miller, Douglas K
[Person:448677] Molineaux, SM
[Person:448687] Weidner, JR
[Person:448698] Aunins, J
created[InstanceEdit:448681] Jupe, S, 2009-11-25
journalNature
modified[InstanceEdit:448729] Jupe, S, 2009-11-25
pages768-74
pubMedIdentifier1574116
titleA novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
volume356
year1992
(literatureReference)[Summation:451674] The IL-1 family of cytokines that interact with the Type 1 I...
[Summation:9012686] Interleukin-18 isoform 2 (IL18-2 or pre-IL18 alpha isoform) ...
[Summation:9012691] Interleukin-18 (IL18) is suggested to be cleaved by Caspase-...
[Summation:9012697] Interleukin-18-2 (37-189) (Conti et al. 1997) and IL18 (1-36...
[Summation:9012806] Interleukin-18 isoform 2 (IL18-2 or pre-IL18 alpha isoform) ...
[Summation:9012821] Interleukin-18-2 (37-189) (Conti et al. 1997) and IL18 (1-36...
[Reaction:448703] Interleukin-1 family precursors are cleaved by caspase-1 [Homo sapiens]
[Reaction:5660663] Caspase-8 cleaves IL1B precursor [Homo sapiens]
[BlackBoxEvent:9012096] TRAF6 binds IRAK1:TRAF6 [Homo sapiens]
[BlackBoxEvent:9012500] IL18-2(1-36) and IL18-2(37-189) dissociates from IL18-2(1-36):IL18-2(37-189):2x(CASP1(120-197):CASP1(317-404)) [Homo sapiens]
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