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Details on Person Interleukin-27 translocates from the ER lumen to the extracellular region

Class:Id	BlackBoxEvent:448421
_displayName	Interleukin-27 translocates from the ER lumen to the extracellular region
_doRelease	TRUE
_timestamp	2017-09-12 14:32:03
authored	[InstanceEdit:448455] Jupe, S, 2009-11-24
compartment	[Compartment:984] extracellular region [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:448455] Jupe, S, 2009-11-24
edited	[InstanceEdit:6788465] Garapati, Phani Vijay, 2015-07-21
input	[Complex:8950372] IL27:EBI3 [endoplasmic reticulum lumen] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:448474] IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells
modified	[InstanceEdit:6804715] Jupe, Steve, 2015-10-14 [InstanceEdit:6809137] Garapati, Phani Vijay, 2015-11-09 [InstanceEdit:6809167] Garapati, Phani Vijay, 2015-11-09 [InstanceEdit:8950688] Duenas, Corina, 2016-12-02 [InstanceEdit:9006072] Duenas, Corina, 2017-05-12 [InstanceEdit:9006961] Jupe, Steve, 2017-05-24 [InstanceEdit:9020957] Jupe, Steve, 2017-09-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Interleukin-27 translocates from the ER lumen to the extracellular region IL27:EBI3 (IL27) is secreted to the extracellular space
output	[Complex:448442] IL27:EBI3 [extracellular region] [Homo sapiens]
releaseDate	2015-12-15
releaseStatus	NEW
reviewed	[InstanceEdit:6809153] Narazaki, M, Tanaka, M, 2015-11-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6812275] R-HSA-448421.6
summation	[Summation:448422] When Interleukin-27 subunit beta (EBI3) was expressed in cel...
(hasEvent)	[Pathway:9020956] Interleukin-27 signaling [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9781732] Update Tracker - [BlackBoxEvent:448421] Interleukin-27 translocates from the ER lumen to the extracellular region - v60:[add_removeInput, modifyText]
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