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Details on Person AMPK phosphorylation of raptor mediates a metabolic checkpoint

Class:Id	LiteratureReference:447068
_displayName	AMPK phosphorylation of raptor mediates a metabolic checkpoint
_timestamp	2009-11-20 13:05:57
author	[Person:447075] Gwinn, DM [Person:447078] Shackelford, DB [Person:447076] Egan, DF [Person:447069] Mihaylova, MM [Person:447070] Mery, A [Person:447072] Vasquez, DS [Person:447073] Turk, BE [Person:380962] Shaw, RJ
created	[InstanceEdit:447077] Jassal, Bijay, 2009-11-20
journal	Mol Cell
pages	214-26
pubMedIdentifier	18439900
title	AMPK phosphorylation of raptor mediates a metabolic checkpoint
volume	30
year	2008
(literatureReference)	[Reaction:447074] AMPK phosphorylates Raptor in the mTORC1 complex [Homo sapiens] [Reaction:5672017] Rheb in the MTORC1 complex hydrolyses GTP [Homo sapiens] [Reaction:5673768] p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex [Homo sapiens] [Summation:5655426] mTORC1 integrates four major signals – growth factors, energ... [Summation:5672128] When cellular energy is depleted AMPK is activated and inhib... [Summation:5672814] Under nutrient-rich conditions, the mTORC1 complex associate... [Summation:5675703] When cellular energy is depleted, the active AMPK complex (b...
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