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Details on Person cAMP Induces dissociation of active protein kinase A subunits from the PKA:Akap150:Iqgap1 complex

Class:Id	Reaction:446974
_displayName	cAMP Induces dissociation of active protein kinase A subunits from the PKA:Akap150:Iqgap1 complex
_doRelease	TRUE
_timestamp	2010-12-02 14:37:23
authored	[InstanceEdit:446962] May, B, 2009-11-19
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:446973] May, B, 2009-11-19
edited	[InstanceEdit:446962] May, B, 2009-11-19
input	[SimpleEntity:30389] cAMP [cytosol] [SimpleEntity:30389] cAMP [cytosol] [SimpleEntity:30389] cAMP [cytosol] [SimpleEntity:30389] cAMP [cytosol] [Complex:446967] PKA:Akap150,79:Iqgap1 [plasma membrane] [Rattus norvegicus]
isChimeric	FALSE
literatureReference	[LiteratureReference:381726] Identification of an IQGAP1/AKAP79 complex in beta-cells [LiteratureReference:446968] Targeted protein kinase A and PP-2B regulate insulin secretion through reversible phosphorylation [LiteratureReference:446978] Cell-permeable peptide-based disruption of endogenous PKA-AKAP complexes: a tool for studying the molecular roles of AKAP-mediated PKA subcellular anchoring [LiteratureReference:446982] Anchoring of protein kinase A facilitates hormone-mediated insulin secretion
modified	[InstanceEdit:446994] May, B, 2009-11-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	cAMP Induces dissociation of active protein kinase A subunits from the PKA:Akap150:Iqgap1 complex
output	[CandidateSet:446977] Protein kinase A catalytic subunit (rat) [cytosol] [Rattus norvegicus] [CandidateSet:446977] Protein kinase A catalytic subunit (rat) [cytosol] [Rattus norvegicus] [Complex:446992] PKA regulatory subunit:cAMP:Akap150,79:Iqgap1 [plasma membrane] [Rattus norvegicus]
releaseDate	2009-12-15
reviewed	[InstanceEdit:446962] May, B, 2009-11-19
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48895] Rattus norvegicus
stableIdentifier	[StableIdentifier:1105041] R-RNO-446974.2
summation	[Summation:446991] The regulatory subunits of protein kinase A bind cAMP which ...
(inferredFrom)	[Reaction:381707] PKA:AKAP79:IQGAP1 complex dissociates to active PKA subunits in response to cAMP [Homo sapiens]
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No pathways have been reviewed or authored by cAMP Induces dissociation of active protein kinase A subunits from the PKA:Akap150:Iqgap1 complex (446974)