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Details on Person Activation of G(s) by the Glucagon-like peptide-1 receptor (Glp1r, rat)

Class:Id	Reaction:446954
_displayName	Activation of G(s) by the Glucagon-like peptide-1 receptor (Glp1r, rat)
_doRelease	TRUE
_timestamp	2010-12-02 14:34:37
authored	[InstanceEdit:446943] May, B, 2009-11-19
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:446958] May, B, 2009-11-19
edited	[InstanceEdit:446943] May, B, 2009-11-19
input	[Complex:446930] GLP-1:Glp1r:G(s):GDP [plasma membrane] [Rattus norvegicus] [SimpleEntity:29438] GTP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:446955] Different domains in the third intracellular loop of the GLP-1 receptor are responsible for Galpha(s) and Galpha(i)/Galpha(o) activation [LiteratureReference:446952] Different role of intracellular loops of glucagon-like peptide-1 receptor in G-protein coupling [LiteratureReference:446928] Pancreatic glucagon-like peptide-1 receptor couples to multiple G proteins and activates mitogen-activated protein kinase pathways in Chinese hamster ovary cells
modified	[InstanceEdit:446962] May, B, 2009-11-19 [InstanceEdit:447053] May, B, 2009-11-20 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Activation of G(s) by the Glucagon-like peptide-1 receptor (Glp1r, rat)
output	[SimpleEntity:29420] GDP [cytosol] [Complex:446961] GLP-1:Glp1r:G(s):GTP [plasma membrane] [Rattus norvegicus]
releaseDate	2009-12-15
reviewed	[InstanceEdit:446943] May, B, 2009-11-19
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48895] Rattus norvegicus
stableIdentifier	[StableIdentifier:1104553] R-RNO-446954.2
summation	[Summation:446931] Binding of Glucagon-like peptide-1 to the Glucagon-like pept...
(inferredFrom)	[Reaction:381706] GLP1R:GLP1 activates G(s) [Homo sapiens]
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No pathways have been reviewed or authored by Activation of G(s) by the Glucagon-like peptide-1 receptor (Glp1r, rat) (446954)