Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person TRAF6 is K63 poly-ubiquitinated

Class:IdReaction:446877
_displayNameTRAF6 is K63 poly-ubiquitinated
_doReleaseTRUE
_timestamp2017-09-11 14:12:33
authored[InstanceEdit:744679] Ray, KP, 2010-05-17
catalystActivity[CatalystActivity:450164] ubiquitin-protein transferase activity of hp-IRAK1:3xTRAF6:3xUBE2N:UBE2V1:K63polyUb [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:446872] Jupe, S, 2009-11-18
edited[InstanceEdit:744683] Jupe, S, 2010-05-17
input[Complex:8948014] hp-IRAK1:3xTRAF6:3xUBE2N:UBE2V1:K63polyUb [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:202511] Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation
modified[InstanceEdit:446897] Jupe, S, 2009-11-18
[InstanceEdit:450149] Jupe, S, 2009-12-16
[InstanceEdit:450189] Jupe, S, 2009-12-16
[InstanceEdit:744685] Jupe, S, 2010-05-17
[InstanceEdit:772535] Jupe, S, 2010-05-21
[InstanceEdit:804979] Jupe, S, 2010-05-26
[InstanceEdit:8948020] Jupe, Steve, 2016-11-08
[InstanceEdit:9020703] Jupe, Steve, 2017-09-11
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameTRAF6 is K63 poly-ubiquitinated
output[Complex:450144] hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] [Homo sapiens]
releaseDate2010-06-15
reviewed[InstanceEdit:744680] Pinteaux, E, 2010-05-17
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1104910] R-HSA-446877.4
summation[Summation:202446] TRAF6 possesses ubiquitin ligase activity and undergoes K-63...
(hasEvent)[Pathway:9020702] Interleukin-1 signaling [Homo sapiens]
(updatedInstance)[_UpdateTracker:9782127] Update Tracker - [Reaction:446877] TRAF6 is K63 poly-ubiquitinated - v59:[add_removeInput, removeOutput]
[_UpdateTracker:9788187] Update Tracker - [Reaction:446877] TRAF6 is K63 poly-ubiquitinated - v43:[modifyText]
[_UpdateTracker:9789949] Update Tracker - [Reaction:446877] TRAF6 is K63 poly-ubiquitinated - v36:[modifyText]
[Change default viewing format]
No pathways have been reviewed or authored by TRAF6 is K63 poly-ubiquitinated (446877)