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Details on Person Jupe, S, 2009-11-18
| Class:Id | InstanceEdit:446872 |
| _displayName | Jupe, S, 2009-11-18 |
| _timestamp | 2009-11-18 17:20:49 |
| author | [Person:391309] Jupe, Steve |
| dateTime | 2009-11-18 22:19:37 |
| (created) | [LiteratureReference:446861] Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor [Reaction:446862] Hyperphosphorylated IRAK1 associates with TRAF6 [Homo sapiens] [Summation:446863] Hyperphosphorylated IRAK1, still within the receptor complex... [Complex:446864] IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1:TRAF6 [plasma membrane] [Homo sapiens] [Person:446865] Kurama, T [Person:446866] Aebi, N [LiteratureReference:446867] Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4 [Reaction:446868] The Interleukin 1 receptor complex binds Tollip [Homo sapiens] [Person:446869] Takeuchi, M [Reaction:446870] Polyubiquitinated TRAF6 binds the TAK1 complex [Homo sapiens] |
| (modified) | [LiteratureReference:165896] Sequential autophosphorylation steps in the interleukin-1 Receptor-associated Kinase-1 Regulate its Availability as an Adapter in Interleukin-1 Signaling [Complex:202463] UBE2N:UBE2V1 [cytosol] [Homo sapiens] [Reaction:446634] IRAK4 is activated by autophosphorylation [Homo sapiens] [Complex:446643] IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP [plasma membrane] [Homo sapiens] [Pathway:446652] Interleukin-1 family signaling [Homo sapiens] [Complex:446689] IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-S376,T378-IRAK1 [plasma membrane] [Homo sapiens] [CatalystActivity:446690] protein serine/threonine kinase activity of IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:IRAK1 [plasma membrane] [Complex:446693] IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:IRAK1 [plasma membrane] [Homo sapiens] [Complex:446696] IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1 [plasma membrane] [Homo sapiens] [Reaction:446701] IRAK4-activated IRAK1 autophosphorylates [Homo sapiens] |
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No pathways have been reviewed or authored by Jupe, S, 2009-11-18 (446872)