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Details on Person Polyubiquitinated TRAF6 binds the TAK1 complex

Class:Id	Reaction:446870
_displayName	Polyubiquitinated TRAF6 binds the TAK1 complex
_doRelease	TRUE
_timestamp	2017-09-11 14:12:04
authored	[InstanceEdit:744679] Ray, KP, 2010-05-17
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:446872] Jupe, S, 2009-11-18
edited	[InstanceEdit:744683] Jupe, S, 2010-05-17
input	[Complex:446878] TAK1 complex [cytosol] [Homo sapiens] [Complex:8948065] hp-IRAK1:3xK63polyUb-TRAF6 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:208287] TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway
modified	[InstanceEdit:446897] Jupe, S, 2009-11-18 [InstanceEdit:447015] Jupe, S, 2009-11-19 [InstanceEdit:450189] Jupe, S, 2009-12-16 [InstanceEdit:744684] Jupe, S, 2010-05-17 [InstanceEdit:8948020] Jupe, Steve, 2016-11-08 [InstanceEdit:8948068] Jupe, Steve, 2016-11-10 [InstanceEdit:9020703] Jupe, Steve, 2017-09-11 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Polyubiquitinated TRAF6 binds the TAK1 complex
output	[Complex:450185] hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] [Homo sapiens]
releaseDate	2010-06-15
reviewed	[InstanceEdit:744680] Pinteaux, E, 2010-05-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105382] R-HSA-446870.4
summation	[Summation:447018] TAK1-binding protein 2 (TAB2) and/or TAB3, as part of a comp...
(hasEvent)	[Pathway:9020702] Interleukin-1 signaling [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9776474] Update Tracker - [Reaction:446870] Polyubiquitinated TRAF6 binds the TAK1 complex - v76:[modifyText] [_UpdateTracker:9782685] Update Tracker - [Reaction:446870] Polyubiquitinated TRAF6 binds the TAK1 complex - v59:[add_removeInput] [_UpdateTracker:9788280] Update Tracker - [Reaction:446870] Polyubiquitinated TRAF6 binds the TAK1 complex - v43:[modifyText] [_UpdateTracker:9790069] Update Tracker - [Reaction:446870] Polyubiquitinated TRAF6 binds the TAK1 complex - v35:[modifyText]
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