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Details on Person IRAK1 binds to MYD88 within the IL1R complex

Class:Id	Reaction:446692
_displayName	IRAK1 binds to MYD88 within the IL1R complex
_doRelease	TRUE
_timestamp	2017-09-11 14:11:00
authored	[InstanceEdit:744679] Ray, KP, 2010-05-17
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:446679] Jupe, S, 2009-11-16
edited	[InstanceEdit:744683] Jupe, S, 2010-05-17
input	[Complex:446643] IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:446639] IRAK1 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:165868] MyD88: an adapter that recruits IRAK to the IL-1 receptor complex [LiteratureReference:446699] IRAK: a kinase associated with the interleukin-1 receptor
modified	[InstanceEdit:446708] Jupe, S, 2009-11-16 [InstanceEdit:450128] Jupe, S, 2009-12-14 [InstanceEdit:744684] Jupe, S, 2010-05-17 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:9020703] Jupe, Steve, 2017-09-11 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	IRAK1 binds to MYD88 within the IL1R complex
output	[Complex:446693] IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:IRAK1 [plasma membrane] [Homo sapiens]
releaseDate	2010-06-15
reviewed	[InstanceEdit:744680] Pinteaux, E, 2010-05-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105308] R-HSA-446692.3
summation	[Summation:450116] MYD88 recruits unphosphorylated, inactive IRAK1 to the IL1 r...
(hasEvent)	[Pathway:9020702] Interleukin-1 signaling [Homo sapiens]
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No pathways have been reviewed or authored by IRAK1 binds to MYD88 within the IL1R complex (446692)